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| CSGID ID | Priority | Locus Tag | NCBI GI | Gene Name |
Common Name | Sequence Length |
Comment | Project | Homolog PDB ID |
Homolog Sequence Identity |
Target Organism | TIGR Main Role | TIGR Subrole | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IDP00128 | 1 | NT01ST3027 | 16765755 | pdxK | mp65f07.r1 Soares_thymus_2NbMT Mus muscu... | 288 | Essential | October 2007 | 2DDM | 65.6% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridoxine | |||||||||||||||||
| IDP02781 | 1 | GBAA4693 | 47529992 | hemL-2 | glutamate-1-semialdehyde aminotransferas... | 429 | N/A | June 2008 | 2CFB | 59.4% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00092 | 1 | NT01SF0466 | 30040219 | hemH | ferrochelatase | 320 | Essential | October 2007 | 1L8X | 29.4% | Shigella flexneri | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP01820 | 1 | GBAA5463 | 47530777 | thiC | thiamine biosynthesis protein ThiC [Baci... | 586 | N/A | June 2008 | 3EPM | 67.9% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Thiamine | |||||||||||||||||
| IDP02564 | 1 | GBAA0084 | 47525340 | ispD | 2-C-methyl-D-erythritol 4-phosphate cyti... | 226 | Lance Stewart drug target | June 2008 | 1W77 | 36.7% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP02800 | 1 | GBAA4828 | 47530124 | coaE | dephospho-CoA kinase [Bacillus anthracis... | 200 | Lance Stewart drug target | June 2008 | 1JJV | 43.5% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP00991 | 1 | STM2212 | 16765541 | yeiR | putative cobalamin biosynthetic protein ... | 328 | Conserved Gene / Pathway | March 2008 | 1NIJ | 18.9% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP01839 | 1 | GBAA1563 | 47526836 | panC | pantoate--beta-alanine ligase [Bacillus ... | 282 | N/A | June 2008 | 2EJC | 50.7% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | |||||||||||||||||
| IDP02528 | 1 | GBAA4405 | 47529699 | folD | methylenetetrahydrofolate dehydrogenase/... | 286 | N/A | June 2008 | 1B0A | 49% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP00932 | 1 | STM0645 | 16764022 | nadD | nicotinic acid mononucleotide adenyltran... | 213 | Conserved Gene / Pathway | March 2008 | 1K4K | 85.4% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridine nucleotides | |||||||||||||||||
| IDP01069 | 1 | STM3938 | 16767209 | hemC | porphobilinogen deaminase | 318 | Conserved Gene / Pathway | March 2008 | 1AH5 | 87.7% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP02721 | 1 | GBAA4007 | 47529300 | coaBC | bifunctional phosphopantothenoylcysteine... | 401 | N/A | June 2008 | 1U7U | 23.2% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | |||||||||||||||||
| IDP02834 | 1 | GBAA4975 | 47530273 | moaC | molybdenum cofactor biosynthesis protein... | 161 | N/A | June 2008 | 2EEY | 69.6% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Molybdopterin | |||||||||||||||||
| IDP01038 | 1 | STM2929 | 16766235 | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosp... | 159 | Drug Target Function | March 2008 | 1GX1 | 98.1% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP01034 | 1 | STM4089 | 16767355 | menG | ribonuclease activity regulator protein ... | 161 | Conserved Gene / Pathway | March 2008 | 1Q5X | 97.5% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP00937 | 1 | STM0795 | 16764158 | bioF | 8-amino-7-oxononanoate synthase | 385 | Conserved Gene / Pathway | March 2008 | 1BS0 | 80% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP02768 | 1 | GBAA4689 | 47529988 | folC | folylpolyglutamate synthase [Bacillus an... | 433 | N/A | June 2008 | 1O5Z | 34.6% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP02735 | 1 | GBAA4334 | 47529631 | ribH | riboflavin synthase subunit beta [Bacill... | 153 | N/A | June 2008 | 1RVV | 72.5% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP01675 | 1 | GBAA5217 | 47530523 | ABC transporter ATP-binding protein [Bac... | 261 | N/A | June 2008 | 2D2E | 57.5% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | ||||||||||||||||||
| IDP01704 | 1 | GBAA5215 | 47530521 | aminotransferase, class V [Bacillus anth... | 406 | N/A | June 2008 | 1T3I | 51% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | ||||||||||||||||||
| IDP02213 | 1 | GBAA0068 | 47525322 | pabB | para-aminobenzoate synthase component I ... | 465 | N/A | June 2008 | 1QDL | 37.2% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP01079 | 1 | STM4167 | 16767421 | hemE | uroporphyrinogen decarboxylase | 354 | Essential Gene | March 2008 | 1JPH | 47.7% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP02332 | 1 | GBAA1462 | 47526735 | UbiE/COQ5 family methlytransferase [Baci... | 258 | N/A | June 2008 | 2GH1 | 19.8% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | ||||||||||||||||||
| IDP00017 | 1 | BA_4333 | 81581445 | ribBA | Riboflavin biosynthesis protein ribBA [I... | 397 | Drug Target Homolog | October 2007 | 2BZ0 | 27% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP00439 | 1 | YPO2930 | 16123117 | pdxJ | pyridoxal phosphate biosynthetic protein... | 243 | Virulence Associated Factor | March 2008 | 3F4N | 100% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridoxine | |||||||||||||||||
| IDP00230 | 1 | YPO3444 | 16123592 | - | putative acetyltransferase | 167 | Virulence | October 2007 | 2GE3 | 18% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP01059 | 1 | STM3509 | 16766797 | bioH | carboxylesterase BioH | 256 | Drug Target Function | March 2008 | 1M33 | 79.3% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP00412 | 1 | YPO0169 | 16120512 | pabA | para-aminobenzoate synthase component II... | 191 | Drug Target Function | March 2008 | 1QDL | 47.1% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP01232 | 1 | BA_5112 | 30259596 | menF | menaquinone-specific isochorismate synth... | 464 | Drug Target Function | March 2008 | 2EUA | 21.3% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP02260 | 1 | GBAA0072 | 47777774 | folB | dihydroneopterin aldolase [Bacillus anth... | 120 | N/A | June 2008 | 1DHN | 43.3% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP02280 | 1 | GBAA0531 | 47525801 | hemL-1 | glutamate-1-semialdehyde aminotransferas... | 434 | N/A | June 2008 | 2E7U | 48.6% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00895 | 1 | STM1165 | 16764521 | grxB | glutaredoxin 2 | 215 | Conserved Gene / Pathway | March 2008 | 1G7O | 86% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Glutathione and analogs | |||||||||||||||||
| IDP00527 | 1 | YPO0129 | 16120472 | bioH | putative biotin biosynthesis protein | 258 | Drug Target Function | March 2008 | 1M33 | 63.6% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP00745 | 1 | SACOL1715 | 57284726 | hemB | delta-aminolevulinic acid dehydratase | 324 | Drug Target Function | March 2008 | 1B4E | 47.8% | Staphylococcus aureus | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00746 | 1 | SACOL1717 | 57284728 | hemC | porphobilinogen deaminase | 308 | Drug Target Function | March 2008 | 1PDA | 45.1% | Staphylococcus aureus | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00960 | 1 | STM1310 | 16764661 | nadE | NAD synthetase | 275 | Drug Target Function | March 2008 | 1WXE | 89.5% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridine nucleotides | |||||||||||||||||
| IDP00534 | 1 | YPO3367 | 16123517 | cysG | siroheme synthase | 472 | Conserved Gene / Pathway | March 2008 | 1PJQ | 52.5% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP02777 | 1 | GBAA4698 | 47529997 | hemA | glutamyl-tRNA reductase [Bacillus anthra... | 444 | N/A | June 2008 | 1GPJ | 27.3% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00936 | 1 | STM0793 | 16764156 | bioA | adenosylmethionine--8-amino-7-oxononanoa... | 429 | Conserved Gene / Pathway | March 2008 | 1MLY | 86.2% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP00643 | 1 | SACOL2638 | 57286542 | precorrin-2 dehydrogenase | 201 | Conserved Gene / Pathway | March 2008 | 3DFZ | 33.8% | Staphylococcus aureus | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | ||||||||||||||||||
| IDP00308 | 1 | CBU_0288 | 29653640 | coaD | phosphopantetheine adenylyltransferase | 159 | Drug Target Function | March 2008 | 1OD6 | 47.2% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | |||||||||||||||||
| IDP01012 | 1 | STM2578 | 16765898 | pdxJ | pyridoxal phosphate biosynthetic protein... | 243 | Conserved Gene / Pathway | March 2008 | 1M5W | 93.8% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridoxine | |||||||||||||||||
| IDP01749 | 1 | Cj1224 | 6968651 | ribA | putative riboflavin synthase alpha chain... | 199 | N/A | June 2008 | 1A7D | 18.1% | Campylobacter jejuni | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP00941 | 1 | STM0846 | 16764208 | moeA | molybdopterin biosynthesis protein MoeA ... | 413 | Conserved Gene / Pathway | March 2008 | 1FC5 | 87.2% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Molybdopterin | |||||||||||||||||
| IDP01753 | 1 | CBU_0423 | 29541032 | panC | pantoate--beta-alanine ligase [Coxiella ... | 257 | N/A | June 2008 | 1MOP | 37% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | |||||||||||||||||
| IDP01663 | 1 | GBAA4696 | 47529995 | hemC | porphobilinogen deaminase [Bacillus anth... | 309 | N/A | June 2008 | 3ECR | 48.2% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Heme, porphyrin, and cobalamin | |||||||||||||||||
| IDP00969 | 1 | STM1597 | 161353598 | ydcW | putative aldehyde dehydrogenase | 474 | Conserved Gene / Pathway | March 2008 | 1WNB | 83.5% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP00580 | 1 | YPO0059 | 16120412 | kbl | 2-amino-3-ketobutyrate coenzyme A ligase... | 403 | Conserved Gene / Pathway | March 2008 | 1FC4 | 82.9% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP02565 | 1 | CBU_0648 | 29541249 | ribH | 6,7-dimethyl-8-ribityllumazine synthase ... | 151 | N/A | June 2008 | 1RVV | 45% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP01948 | 1 | STM1931 | 16765272 | araH | putative intracellular protease/amidase ... | 185 | N/A | June 2008 | 3B36 | 30.8% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Thiamine | |||||||||||||||||
| IDP00875 | 1 | STM1374 | 16764724 | ynhA | cysteine desufuration protein SufE | 138 | Conserved Gene / Pathway | March 2008 | 1MZG | 87.7% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP01647 | 1 | CBU_0795 | 29541389 | folE | GTP cyclohydrolase I [Coxiella burnetii ... | 184 | N/A | June 2008 | 1WM9 | 56% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP01044 | 1 | STM3070 | 16766371 | epd | D-erythrose 4-phosphate dehydrogenase | 348 | Conserved Gene / Pathway | March 2008 | 1OBF | 47.1% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridoxine | |||||||||||||||||
| IDP00940 | 1 | STM0845 | 16764207 | moeB | molybdopterin biosynthesis protein MoeB ... | 249 | Conserved Gene / Pathway | March 2008 | 1JW9 | 88.8% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Molybdopterin | |||||||||||||||||
| IDP00979 | 1 | STM1953 | 16765291 | yedO | D-cysteine desulfhydrase | 328 | Conserved Gene / Pathway | March 2008 | 1J0A | 38.7% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Pyridoxine | |||||||||||||||||
| IDP02165 | 1 | CBU_1993 | 29542548 | folA | dihydrofolate reductase [Coxiella burnet... | 161 | N/A | June 2008 | 1ZDR | 46.6% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP00920 | 1 | STM0417 | 16763797 | ribH | riboflavin synthase subunit beta | 156 | Conserved Gene / Pathway | March 2008 | 1RVV | 51.9% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP01735 | 1 | CBU_1129 | 29541703 | nifS | cysteine desulfurase [Coxiella burnetii ... | 396 | N/A | June 2008 | 1P3W | 57.1% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP00424 | 1 | YPO2975 | 16123156 | aminotransferase | 411 | Conserved Gene / Pathway | March 2008 | 2DOU | 33.8% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Thiamine | ||||||||||||||||||
| IDP02629 | 1 | CBU_1006 | 29541588 | bioF | 8-amino-7-oxononanoate synthase [Coxiell... | 384 | N/A | June 2008 | 1BS0 | 37.8% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP00759 | 1 | SACOL0188 | 57285390 | ggt | gamma-glutamyltranspeptidase | 668 | Drug Target Function | March 2008 | 2E0W | 27.8% | Staphylococcus aureus | Biosynthesis of cofactors, prosthetic groups, and carriers | Glutathione and analogs | |||||||||||||||||
| IDP02196 | 1 | GBAA0734 | 47526018 | thiD-1 | phosphomethylpyrimidine kinase [Bacillus... | 270 | N/A | June 2008 | 2I5B | 48.1% | Bacillus anthracis | Biosynthesis of cofactors, prosthetic groups, and carriers | Thiamine | |||||||||||||||||
| IDP02012 | 1 | STM4233 | 16767483 | ubiC | chorismate pyruvate lyase [Salmonella ty... | 165 | N/A | June 2008 | 1G1B | 86.1% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP02171 | 1 | CBU_0894 | 29541483 | folC | FolC bifunctional protein [Coxiella burn... | 416 | N/A | June 2008 | 1W78 | 42.5% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Folic acid | |||||||||||||||||
| IDP00926 | 1 | STM0597 | 16763974 | entB | 2,3-dihydro-2,3-dihydroxybenzoate synthe... | 285 | Conserved Gene / Pathway | March 2008 | 2FQ1 | 88.4% | Salmonella typhimurium | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP02559 | 1 | YPO3325 | 16123478 | dmsA | anaerobic dimethyl sulfoxide reductase c... | 816 | N/A | June 2008 | 1E60 | 28.7% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Biotin | |||||||||||||||||
| IDP00402 | 1 | YPO3182 | 16123344 | ribH | riboflavin synthase subunit beta | 156 | Conserved Gene / Pathway | March 2008 | 1RVV | 50.6% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Riboflavin, FMN, and FAD | |||||||||||||||||
| IDP02069 | 1 | CBU_2017 | 29542571 | ubiE | ubiquinone/menaquinone biosynthesis meth... | 250 | N/A | June 2008 | 3DH0 | 18.4% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP02823 | 1 | CBU_0382 | 29540992 | ispB | octylprenyl diphosphate synthase-like pr... | 332 | N/A | June 2008 | 1WY0 | 31.6% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP02019 | 1 | CBU_1182 | 29541752 | iscS | cysteine desulfurase [Coxiella burnetii ... | 380 | N/A | June 2008 | 1P3W | 43.9% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Other | |||||||||||||||||
| IDP00582 | 1 | YPO2528 | 16122747 | menF | menaquinone-specific isochorismate synth... | 455 | Conserved Gene / Pathway | March 2008 | 2EUA | 51.2% | Yersinia pestis | Biosynthesis of cofactors, prosthetic groups, and carriers | Menaquinone and ubiquinone | |||||||||||||||||
| IDP02089 | 1 | CBU_0424 | 29541033 | panB | 3-methyl-2-oxobutanoate hydroxymethyltra... | 266 | N/A | June 2008 | 1OY0 | 42.5% | Coxiella burnetii | Biosynthesis of cofactors, prosthetic groups, and carriers | Pantothenate and coenzyme A | |||||||||||||||||
| IDP01619 | 1 | CBU_1871 | 29542425 | pabA | para-aminobenzoate synthase glutamine am... | 201 | N/A | June 2008 | 1QDL | 44.3% | ||||||||||||||||||||