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Target   IDP00665

Stage
in_crystallization_trials  
Locus Tag/Selection DB Lookup
SACOL1079  
NCBI Protein Lookup
gi: 57285865   accession: YP_185943  
PATRIC Lookup
19528392  
Organism
Staphylococcus aureus subsp. aureus COL  
Common Name
amidophosphoribosyltransferase  
Gene Name
purF  
NCBI Annotation
identified by match to protein family HMM PF00156; match to protein family HMM PF00310; match to protein family HMM TIGR01134  
Selection Phase
Phase 2: March 2008  
Date Approved
Apr 15, 2008  
Justification for Selection
Drug Target Function  
Priority
7  
Sequence Length
494  
(Subtargets)
 
pI
6.56  
Molecular Weight
54.4 kDa  
Sequence
MFNYSGLNEE CGVFGIWNHP EAAQLTYMGL HSLQHRGQEG AGIVVSDQNE LKGERGLGLL TEAIKDDQME RLKGYQHAIG HVRYATSGNK GIENIQPFLY HFYDMSVGIC HNGNLINAKS LRQNLEKQGA IFHSSSDTEV IMHLIRRSKA PTFEEALKES LRKVKGGFTF AILTKDALYG AVDPNAIRPL VVGKMKDGTY ILASETCAID VLGAEFVQDI HAGEYVVIND KGITVKSYTH HTTTAISAME YIYFARPDST IAGKNVHAVR KASGKKLAQE SPVNADMVIG VPNSSLSAAS GYAEEIGLPY EMGLVKNQYV ARTFIQPTQE LREQGVRVKL SAVKDIVDGK NIILVDDSIV RGTTIRRIVK MLKDSGANKV HVRIASPEFM FPSFYGIDVS TTAELISASK SPEEIKDYIG ADSLAYLSVD GLIESIGLDY DAPYSGLCVE SFTGDYPAGL YDYEANYKAH LSHRQKQYIS KNKHFFDSEG NLNV  
DNA Sequence
ATGTTT AACTAC TCAGGA TTAAAC GAAGAA TGTGGC GTGTTT GGTATT TGGAAT CATCCT GAAGCA GCGCAA CTAACA TATATG GGACTT CATAGT TTGCAA CATCGT GGTCAA GAAGGT GCAGGT ATAGTT GTTTCT GATCAA AATGAA TTAAAA GGCGAG CGAGGA TTAGGC TTACTA ACTGAA GCGATT AAAGAT GATCAA ATGGAA CGATTA AAAGGA TATCAA CATGCA ATTGGT CACGTC CGTTAT GCTACT TCAGGT AATAAA GGTATT GAAAAT ATTCAA CCGTTT CTGTAT CACTTT TATGAT ATGAGT GTAGGT ATTTGT CATAAT GGTAAC CTCATT AATGCT AAATCA TTGCGT CAGAAT TTAGAA AAACAA GGTGCT ATCTTC CATTCG TCTTCT GATACT GAAGTC ATTATG CATTTG ATACGT CGAAGT AAAGCT CCTACT TTTGAG GAAGCG TTGAAA GAAAGT TTGCGA AAAGTT AAAGGC GGTTTT ACATTT GCGATT TTAACT AAAGAT GCGTTA TATGGC GCAGTA GATCCA AATGCT ATCAGA CCACTT GTTGTA GGTAAA ATGAAA GATGGG ACATAC ATCCTT GCAAGT GAAACA TGTGCA ATAGAT GTGTTA GGTGCA GAATTT GTTCAA GATATT CATGCA GGTGAA TATGTC GTGATT AACGAT AAAGGT ATTACA GTTAAA TCTTAT ACACAT CATACG ACAACT GCAATT TCTGCG ATGGAA TATATT TATTTT GCTAGA CCAGAC TCAACA ATAGCT GGTAAA AATGTC CATGCA GTACGT AAAGCT TCTGGT AAAAAA TTAGCC CAAGAA AGCCCT GTAAAT GCTGAT ATGGTC ATCGGT GTACCC AATTCA TCGCTA TCAGCT GCGAGT GGTTAT GCTGAA GAAATA GGTTTG CCATAT GAAATG GGACTA GTTAAA AATCAA TATGTT GCAAGA ACATTT ATTCAA CCAACT CAAGAA TTACGT GAGCAA GGTGTG AGAGTG AAGTTA TCTGCG GTAAAA GATATA GTAGAT GGGAAA AATATC ATTCTT GTTGAT GATTCC ATTGTT CGCGGT ACGACA ATTCGA CGCATT GTGAAA ATGTTA AAAGAT TCTGGT GCAAAT AAAGTG CATGTG CGTATA GCATCA CCGGAA TTTATG TTTCCA AGTTTT TACGGA ATCGAT GTTTCA ACTACG GCAGAA TTAATT TCTGCA AGCAAA TCACCT GAAGAA ATTAAA GATTAT ATTGGC GCTGAT TCATTA GCATAT CTATCT GTAGAT GGGTTA ATTGAA TCAATT GGTTTA GATTAT GACGCG CCATAT AGTGGC TTATGT GTAGAA AGTTTC ACTGGA GATTAT CCTGCA GGGTTA TATGAT TATGAA GCAAAT TATAAA GCGCAT TTAAGT CATCGA CAAAAG CAATAT ATTTCT AAAAAC AAACAC TTTTTT GATAGC GAGGGA AATTTA AATGTC TAA  
Inserted
Apr 23, 2008