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Target   IDP01329

Stage
in_pdb   : 3HJB
Locus Tag/Selection DB Lookup
VC0374  
NCBI Protein Lookup
gi: 15640401   accession: NP_230028  
PATRIC Lookup
20079819  
Organism
Vibrio cholerae O1 biovar El Tor str. N16961  
Common Name
glucose-6-phosphate isomerase  
Gene Name
pgi  
NCBI Annotation
functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family  
TIGR Main Role/Annotations
Energy metabolism  
TIGR Sub Role
Glycolysis/gluconeogenesis  
Selection Phase
Phase 2: March 2008  
Date Approved
Apr 15, 2008  
Justification for Selection
Drug Target Function  
Priority
7  
Sequence Length
550  
(Subtargets)
 
pI
5.98  
Molecular Weight
60.7 kDa  
Sequence
MLKNINPTQT QAWKALTAHF ESAQDMDLKA LFAQDSERFA KYSARFGQDI LVDYSKNLVN AETMQHLFAL AKETDLQSAI TAMFKGEAIN QTEDRAVLHT ALRNRSNSPV LVNGEDVMPA VNAVLAKMKA FSERVIGGEW KGFTGKAITD VVNIGIGGSD LGPYMVTEAL VPYKNHLTMH FVSNVDGTHM AETLKNVDPE TTLFLVASKT FTTQETMTNA HTARDWFLKA AGDEAHVAKH FAALSTNGKA VAEFGIDTDN MFEFWDWVGG RYSLWSAIGL SIILSIGYDN FVELLAGAHE MDQHFVNTPF ESNIPVILAL IGIWYNNFHG AESEAILPYD QYLHRFAAYF QQGNMESNGK YVDRNGNPVT YQTGPIIWGE PGTNGQHAFY QLIHQGTKLI PCDFIAPAVS HNLVGDHHQK LMSNFFAQTE ALAFGKSAQA VQAELEKAGK SAAEIAALVP FKVFEGNRPT NSILVKQITP RTLGNLIAMY EHKIFVQGVI WNIFSFDQWG VELGKQLANQ ILPELADSAA VTSHDSSTNG LINAFKAFRA  
DNA Sequence
ATGTTG AAAAAT ATCAAT CCAACG CAAACC CAAGCT TGGAAA GCGCTG ACCGCG CATTTT GAATCT GCTCAG GATATG GACCTC AAAGCA CTTTTT GCGCAA GACAGC GAGCGT TTTGCC AAATAC TCTGCG CGCTTT GGTCAG GACATT CTGGTC GATTAT TCGAAA AACCTA GTGAAT GCGGAA ACGATG CAACAC TTGTTT GCGTTG GCTAAA GAAACG GATCTG CAATCT GCCATC ACCGCG ATGTTT AAAGGT GAAGCG ATCAAC CAAACG GAAGAT CGTGCG GTACTG CACACT GCGCTG CGTAAT CGTAGC AATTCA CCTGTG TTGGTG AACGGT GAGGAT GTAATG CCTGCA GTAAAC GCTGTG TTGGCT AAAATG AAAGCC TTCTCT GAGCGT GTGATT GGCGGT GAGTGG AAAGGT TTCACC GGCAAG GCGATT ACTGAT GTCGTT AATATC GGCATT GGTGGC TCCGAT CTCGGT CCTTAC ATGGTC ACAGAA GCTCTG GTGCCT TATAAG AACCAT TTGACC ATGCAC TTTGTG TCAAAC GTCGAT GGTACA CACATG GCGGAG ACACTG AAAAAC GTCGAT CCTGAA ACCACC CTCTTC TTAGTG GCTTCC AAAACT TTCACT ACCCAA GAAACC ATGACC AACGCC CACACG GCTCGT GATTGG TTCTTG AAAGCG GCAGGA GATGAA GCACAT GTTGCT AAGCAC TTTGCG GCGCTA TCAACC AATGGT AAAGCG GTGGCT GAGTTT GGTATC GACACC GACAAC ATGTTT GAATTC TGGGAT TGGGTA GGCGGT CGTTAC TCACTG TGGTCA GCGATT GGTCTT TCTATC ATTCTG TCTATC GGTTAC GACAAC TTTGTT GAGCTG CTGGCG GGGGCG CATGAA ATGGAT CAGCAT TTCGTG AACACG CCGTTT GAAAGT AATATT CCGGTC ATTCTG GCGCTG ATTGGC ATTTGG TATAAC AACTTC CATGGT GCTGAA TCTGAA GCGATC CTGCCT TACGAT CAGTAC CTGCAT CGCTTC GCGGCT TACTTC CAACAA GGCAAT ATGGAG TCTAAT GGTAAG TATGTT GATCGT AATGGC AACCCA GTCACT TACCAA ACGGGC CCAATC ATTTGG GGTGAA CCCGGT ACGAAC GGCCAG CACGCT TTCTAT CAGCTT ATCCAC CAAGGC ACTAAG CTGATC CCATGT GATTTT ATCGCG CCAGCG GTGAGT CATAAT TTGGTT GGCGAT CATCAC CAAAAG CTGATG TCTAAC TTCTTC GCGCAA ACCGAA GCCTTA GCCTTC GGAAAA TCCGCG CAAGCC GTGCAA GCTGAA CTCGAA AAAGCG GGTAAA TCGGCG GCAGAA ATTGCA GCGTTA GTGCCG TTCAAA GTGTTT GAAGGT AACCGC CCAACC AACTCG ATTCTG GTTAAG CAGATT ACGCCA CGCACG CTGGGT AACTTG ATTGCG ATGTAC GAACAC AAAATC TTCGTA CAAGGT GTGATT TGGAAC ATCTTC AGTTTC GATCAA TGGGGC GTGGAA CTGGGT AAGCAA CTGGCG AACCAA ATCCTG CCTGAG TTAGCG GATAGC GCAGCC GTGACG TCACAT GACAGC TCGACC AACGGT CTGATC AACGCC TTTAAA GCGTTT CGCGCC TAA  
Inserted
Apr 23, 2008