Structure of IDP90557

Crystal structure of beta-ketoacyl-acyl carrier protein reductase (FabG) from Vibrio cholerae in complex with NADPH

Edit deposit information
CSGID target
IDP90557 
PDB Id
4I08 (NCBI MMDB
Authors
J.Hou,M.Chruszcz,H.Zheng,T.Osinski,W.F.Anderson,W.Minor,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Jing Hou 
Responsible lab
University of Virginia 
Deposition Date
Nov 16, 2012 
Release Date
Dec 12, 2012 

Annotation

Description
fabG, catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis using NADP(H) as a cofactor.  
Functional assignment
fatty acid synthesis 

Ligands

Ligand code Name Ligand type
EDO crystallization
NDP Nicotinamide adenine dinucleotide phosphate biological
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

Unit cell parameters

Space Group
P 62  
Unit Cell

a=63.94Å, b=63.94Å, c=190.37Å
α=90.00, β=90.00, γ=120.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
47.86-2.06Å (2.12-2.06Å)  
Rall(%)
15.2 
Rwork(%)
15.3 (20.8) 
Rfree(%)
17.1 (25.0) 
Num. observed reflections
26944 (0) 
Num. Rfree reflections
1320 (95) 
Completeness(%)
99.8 (98.1) 

Model parameters

Num Atoms
3552  
Num Waters
1  
Num Hetatoms
282  
Model mean isotropic B factor
38.690Å2  
RMSD bond length
0.000Å  
RMSD bond angle
0.000°  
Filename uploaded
pdb_extract_coord_14785.cif (uploaded on Dec 21, 2012 5:08 PM)  
Inserted
Dec 21, 2012