Structure of IDP91245

Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from Helicobacter pylori 26695

Edit deposit information
CSGID target
IDP91245 
PDB Id
4IJK (NCBI MMDB
Authors
J.Hou,T.Osinski,H.Zheng,I.Shumilin,I.G.Shabalin,S.Shatsman,W.F.Anderson,W.Minor,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Jing Hou 
Responsible lab
University of Virginia 
Deposition Date
Dec 21, 2012 
Release Date
Jan 09, 2013 

Annotation

Description
fabG, catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis using NADP(H) as a cofactor. 
Functional assignment
fatty acid synthesis 

Ligands

Ligand code Name Ligand type
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

Unit cell parameters

Space Group
P 21 21 2  
Unit Cell

a=127.17Å, b=114.64Å, c=69.50Å
α=90.00, β=90.00, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
46.96-2.54Å (2.61-2.54Å)  
Rall(%)
23.7 
Rwork(%)
23.5 (26.0) 
Rfree(%)
27.2 (29.2) 
Num. observed reflections
33218 (1407) 
Num. Rfree reflections
1694 (70) 
Completeness(%)
92.5 (57.3) 

Model parameters

Num Atoms
6806  
Num Waters
94  
Num Hetatoms
95  
Model mean isotropic B factor
27.280Å2  
RMSD bond length
0.013Å  
RMSD bond angle
1.356°  
Filename uploaded
4IJK.pdb (uploaded on Jan 09, 2013 1:26 PM)  
Inserted
Jan 09, 2013