Structure of IDP92622

Co-Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Cryptosporidium parvum and the inhibitor p131

Edit deposit information
CSGID target
IDP92622 
PDB Id
4RV8 (NCBI MMDB
Authors
Y.Kim,M.Makowska-Grzyska,M.Gu,M.Kavitha,L.Hedstrom,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Youngchang Kim 
Responsible lab
Argonne National Laboratory 
Deposition Date
Nov 25, 2014 
Release Date
Dec 31, 2014 

Annotation

Ligands

Ligand code Name Ligand type
IMP biological
131 biological
GOL crystallization
PEG crystallization
CSA modified residue

Structure information

Unit cell parameters

Space Group
P 1 21 1  
Unit Cell

a=89.19Å, b=91.83Å, c=92.02Å
α=90.00, β=103.75, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
40.84-2.05Å (2.08-2.21Å)  
Rall(%)
18.9 
Rwork(%)
18.7 (27.8) 
Rfree(%)
22.9 (33.1) 
Num. observed reflections
94294 (2800) 
Num. Rfree reflections
4724 (139) 
Completeness(%)
99.6 (93.0) 

Model parameters

Num Atoms
9837  
Num Waters
339  
Num Hetatoms
577  
Model mean isotropic B factor
36.080Å2  
RMSD bond length
0.004Å  
RMSD bond angle
0.864°  
RMSD dihedral angle
12.07°
 
Filename uploaded
dep-n.pdb (uploaded on Nov 25, 2014 1:55 PM)  
Inserted
Nov 25, 2014