Structure of IDP92102

Structure of the ornithine aminotransferase from Toxoplasma gondii crystallized in presence of oxidized glutathione reveals partial occupancy of PLP at the protein active site

Edit deposit information
CSGID target
IDP92102 
PDB Id
5EQC (NCBI MMDB
Authors
E.V.Filippova,G.Minasov,K.Flores,H.V.Le,R.B.Silverman,R.L.Mcleod,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Ekaterina Filippova 
Responsible lab
Northwestern University 
Deposition Date
Nov 12, 2015 
Release Date
Feb 24, 2016 

Annotation

Ligands

Ligand code Name Ligand type
BGC crystallization
BTB 2-[bis-(2-hydroxy-ethyl)-amino]-2-hydroxymethyl-propane-1,3-diol crystallization
PEG crystallization
PLP pyridoxal-5'-phosphate biological
BME crystallization
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

Unit cell parameters

Space Group
P 43  
Unit Cell

a=109.41Å, b=109.41Å, c=109.88Å
α=90.00, β=90.00, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
109.41-2.20Å (2.26-2.20Å)  
Rall(%)
14.6 
Rwork(%)
14.5 (17.8) 
Rfree(%)
18.1 (22.5) 
Num. observed reflections
65282 (4778) 
Num. Rfree reflections
3198 (203) 
Completeness(%)
100.0 (100.0) 

Model parameters

Num Atoms
6650  
Num Waters
290  
Num Hetatoms
432  
Model mean isotropic B factor
37.350Å2  
RMSD bond length
0.016Å  
RMSD bond angle
1.915°  
Filename uploaded
92102-oxy-con-c_deposit.pdb (uploaded on Nov 12, 2015 4:57 PM)  
Inserted
Nov 12, 2015