Structure of IDP95479

1.95 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Adenine and NAD

Edit deposit information
CSGID target
IDP95479 
PDB Id
5T8K (NCBI MMDB
Authors
G.Minasov,L.Shuvalova,O.Kiryukhina,I.Dubrovska,B.Bishop,K.Kwon,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
Sep 07, 2016 
Release Date
Sep 28, 2016 

Annotation

Ligands

Ligand code Name Ligand type
CME modified residue
NA Sodium ion crystallization
NAD biological
ADE adenine biological
P6G hexaethylene glycol crystallization
TRS Tris(hydroxymethyl)aminomethane crystallization
GOL crystallization
PEG crystallization
PGE crystallization

Structure information

Unit cell parameters

Space Group
P 1 21 1  
Unit Cell

a=67.69Å, b=182.78Å, c=96.25Å
α=90.00, β=100.58, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
29.92-1.95Å (2.00-1.95Å)  
Rall(%)
14.3 
Rwork(%)
14.1 (23.1) 
Rfree(%)
17.3 (25.6) 
Num. observed reflections
166534 (12268) 
Num. Rfree reflections
8326 (615) 
Completeness(%)
99.9 (100.0) 

Model parameters

Num Atoms
16155  
Num Waters
1925  
Num Hetatoms
2357  
Model mean isotropic B factor
33.030Å2  
RMSD bond length
0.009Å  
RMSD bond angle
1.443°  
Filename uploaded
5t8k.pdb (uploaded on Nov 08, 2016 4:13 PM)  
Inserted
Nov 08, 2016