Structure of IDP95086

Crystal structure of macrolide 2(prime)-phosphotransferase MphH from Brachybacterium faecium in complex with azithromycin

Edit deposit information
CSGID target
IDP95086 
PDB Id
5UXD (NCBI MMDB
Authors
Stogios Pj, Skarina T, Wawrzak Z, Yim V, Savchenko A, Anderson Wf, Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Peter Stogios 
Responsible lab
University of Calgary 
Deposition Date
Feb 22, 2017 
Release Date
 

Annotation

Ligands

Ligand code Name Ligand type
ZIT biological
SO4 crystallization
CL crystallization

Structure information

Unit cell parameters

Space Group
P 1 21 1  
Unit Cell

a=55.05Å, b=81.21Å, c=71.34Å
α=90.00, β=96.83, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
45.35-1.70Å (1.72-1.70Å)  
Rall(%)
18.6 
Rwork(%)
18.5 (29.1) 
Rfree(%)
22.5 (29.5) 
Num. observed reflections
136154 (4736) 
Num. Rfree reflections
4057 (145) 
Completeness(%)
98.0 (100.0) 

Model parameters

Num Atoms
4584  
Num Waters
1252  
Num Hetatoms
1519  
Model mean isotropic B factor
30.820Å2  
RMSD bond length
0.006Å  
RMSD bond angle
1.736°  
RMSD dihedral angle
21.087°
 
Filename uploaded
GW0008_azith_APS_x3_Oct14_2016_refine_20.pdb (uploaded on Feb 22, 2017 2:40 PM)  
Inserted
Feb 22, 2017