Structure of IDP95479

2.65 Angstrom Resolution Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with SAH and NAD

Edit deposit information
CSGID target
IDP95479 
PDB Id
5UTU (NCBI MMDB
Authors
G.Minasov,L.Shuvalova,I.Dubrovska,J.Winsor,J.Stam,K.Kwon,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
Feb 15, 2017 
Release Date
Mar 01, 2017 

Annotation

Ligands

Ligand code Name Ligand type
NAD biological
SAH s-adenosyl-l-homocysteine modified residue
CL crystallization
SO4 crystallization
P33 3,6,9,12,15,18-hexaoxaicosane-1,20-diol crystallization
P6G hexaethylene glycol crystallization
ADN adenosine biological
PEG crystallization

Structure information

Unit cell parameters

Space Group
P 1 21 1  
Unit Cell

a=107.91Å, b=185.83Å, c=121.62Å
α=90.00, β=97.98, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
30.00-2.65Å (2.72-2.65Å)  
Rall(%)
17.2 
Rwork(%)
17.0 (24.9) 
Rfree(%)
20.2 (30.0) 
Num. observed reflections
137236 (10007) 
Num. Rfree reflections
6861 (519) 
Completeness(%)
99.9 (99.8) 

Model parameters

Num Atoms
31423  
Num Waters
931  
Num Hetatoms
1778  
Model mean isotropic B factor
52.200Å2  
RMSD bond length
0.009Å  
RMSD bond angle
1.586°  
Filename uploaded
5utu.pdb (uploaded on Mar 21, 2017 5:57 PM)  
Inserted
Mar 21, 2017