Milestones and Press Coverage


The study of Listeria Monocytogenes ROK Repressor Structures, published in a recent Nature Microbiology paper has been featured on the NIAID website.


July 2016:A Cell paper by a team of CSGID researchers and community collaborators from Washington University in St. Louis identifies the structural basis of Zika virus-specific antibody protection.


A study by CSGID researchers and collaborators on Ebola virus replication has been featured as one of the outstanding NIAID research advances of 2015!


The paper on Ebola virus VP35 coauthored by CSGID reserchers and collaborators has been featured in Cell Reports!


February 2015: Protein AtxA, a global virulence regulator from Bacillus anthracis has been selected as NIAID structure of the month.


IDP01169   NIAID structure of the month

Title: AtxA protein, a virulence regulator from Bacillus anthracis

Authors: J.Osipiuk,L.B.Horton,T.M.Koehler,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

October 2014: Two papers by CSGID researchers appear on covers of scientific journals. "Double trouble - Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments" is featured on the cover of Protein Science. The work on the VP35 Ebola target in collaboration with Gaya Amarasinghe is highlighted on the cover of the special issue of Journal of Molecular Biology on regulation of viral replication and assembly.


March 2014: Protein's Crystal Structure Reveals Role in Life-Threatening Bacteria - a Northwestern University news release


January 2014: Structure of protein PA4794 from Pseudomonas aeruginosa has been selected as NIAID structure of the month. Pseudomonas aeruginosa is a Gram-negative bacterium that is a major cause of potentially life-threatening healthcare-associated infections which exhibits an extraordinary ability to acquire resistance to antibiotics. PA4794 could prove to be a drug discovery target, as it is involved in many aspects of cellular physiology. Understanding PA4794-antibiotic interactions may be useful in facilitating the design of more optimal inhibitors.


July 2013: the structure of protein CpIMPDH from the parasite Cryptosporidium parvum in complex with an optimized inhibitor, determined by researchers from the Center for Structural Genomics of Infectious Diseases, Brandeis University, the University of Georgia, Harvard Medical School and the University of Houston, is featured as the NIAID structure of the month.


July 2012: Orthopoxvirus MHC Class I-like protein determined by CSGID featured as the NIAID structure of the month


IDP00259   NIAID structure of the month

Title: OMCP, Orthopox virus MHC class I-like protein (CPXV018)

Authors: E.Lazear,L.W.Peterson,C.A.Nelson,D.H.Fremont,Center For Structural Genomics Of Infectious Diseases (Csgid)

Protein determined by CSGID featured as the NIAID structure of the month


IDP91634   NIAID structure of the month

Title: 1.92 Angstrom resolution crystal structure of the full-length SpcU in complex with full-length ExoU from the type III secretion system of Pseudomonas aeruginosa

Authors: A.S.Halavaty,D.Borek,Z.Otwinowski,G.Minasov,J.L.Veesenmeyer,G.Tyson,L.Shuvalova,A.R.Hauser,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)

Protein determined by CSGID featured as the NIAID structure of the month


June 2011: Protein determined by CSGID featured as the NIAID structure of the month.


IDP00812   NIAID structure of the month

Title: Crystal Structure of Leukotoxin (LukE) from Staphylococcus aureus subsp. aureus COL.

Authors: G.Minasov,A.Halavaty,L.Shuvalova,I.Dubrovska,J.Winsor,F.Bagnoli,F.Falugi,M.Bottomley,G.Grandi,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)

December 2010: Scientists from SSGCID and CSGID have experimentally determined structures of 500 infectious pathogens

Northwestern University Press Release
UPI news release
News-Medical article


October 2nd, 2010: The CSGID has determined its 250th protein structure.


IDP02821   250th structure

Title: Crystal Structure of ATP-dependent Clp Protease Subunit P from Francisella tularensis

Authors: Y.Kim,M.Zhou,M.Gu,W.F.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

February 2010: Protein determined by CSGID featured as the NIAID structure of the month.


July 2010: The CSGID has determined its 200th protein structure.


IDP00348   200th structure

Title: 1.95 Angstrom crystal structure of a bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase (aroA) from Listeria monocytogenes EGD-e

Authors: A.S.Halavaty,S.H.Light,G.Minasov,L.Shuvalova,K.Kwon,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)

October 2009: Protein determined by CSGID featured as the NIAID structure of the month.


IDP90293   NIAID structure of the month

Title: 2.75 Angstrom Crystal Structure of Enolase 1 from Toxoplasma gondii.

Authors: G.Minasov,J.Ruan,L.Shuvalova,A.Halavaty,H.Ngo,S.Tomavo,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid)

August 13th, 2009: The CSGID has determined its 100th protein structure. For more information, read our press releases: (Northwestern University) (University of Virginia)


IDP00044   100th structure

Title: Crystal structure of BA2930 in complex with CoA

Authors: M.M.Klimecka,M.Chruszcz,T.Skarina,O.Onopryienko,M.Cymborowski,A.Savchenko,A.Edwards,W.Anderson,W.Minor,Center For Structural Genomics Of Infectious Diseases (Csgid)

August 2009: Protein determined by CSGID featured as the NIAID structure of the month.


IDP00038   NIAID structure of the month

Title: CRYSTAL STRUCTURE OF MICROCIN IMMUNITY PROTEIN MCCF FROM BACILLUS ANTHRACIS STR. AMES

Authors: B.Nocek,M.Zhou,K.Kwon,W.Anderson,A.Joachimiak,Center For Structural Genomics Of Infectious Diseases (Csgid)

April 2009: Protein determined by CSGID featured as the NIAID structure of the month.