Structure of IDP90557

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) (G141A) from Vibrio cholerae in complex with NADPH

Edit deposit information
CSGID target
IDP90557 
PDB Id
4WK6 (NCBI MMDB
Authors
J.Hou,H.Zheng,W.F.Anderson,W.Minor,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
Jing Hou 
Responsible lab
University of Virginia 
Deposition Date
Oct 01, 2014 
Release Date
Nov 12, 2014 

Annotation

Description
fabG, catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis using NADP(H) as a cofactor. This is a structure for an inactive mutant. 
Functional assignment
fatty acid synthesis 

Ligands

Ligand code Name Ligand type
1PE crystallization
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

Unit cell parameters

Space Group
P 21 21 21  
Unit Cell

a=79.90Å, b=110.34Å, c=117.48Å
α=90.00, β=90.00, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
27.00-2.21Å (2.26-2.21Å)  
Rall(%)
21.1 
Rwork(%)
20.9 (34.4) 
Rfree(%)
24.1 (33.1) 
Num. observed reflections
52057 (3328) 
Num. Rfree reflections
2498 (165) 
Completeness(%)
98.1 (86.2) 

Model parameters

Num Atoms
6710  
Num Waters
99  
Num Hetatoms
227  
Model mean isotropic B factor
65.280Å2  
RMSD bond length
0.013Å  
RMSD bond angle
1.601°  
Filename uploaded
4WK6.pdb (uploaded on Nov 14, 2014 1:12 PM)  
Inserted
Nov 14, 2014