Bromoperoxidases (bromide peroxidases) catalyze the bromination of organic compounds in the presence of bromide and peroxide. The enzymes are divided into 3 classes: vanadium-containing, heme-containing and metal-containing. The IDP00046 structure of bromoperoxidase from Bacillus anthracis does not contain any cofactors such as metal ions or heme groups. The structure consists of an 8-strand -sheet surrounded by numerous -helices. The active centre located in a deep pocket resembles that of bromoperoxidase A2 from Streptomyces aureofaciens (1BRO.pdb) and contains a catalytic triad of Ser 99, Asp 229 and His 258.