Structure of CPX_52010_52016

Crystal Structure of Nsp16-Nsp10 from SARS-CoV-2 in Complex with 7-methyl-GpppA and S-Adenosylmethionine.

Edit deposit information
CSGID target
CPX_52010_52016 
PDB Id
6WVN (NCBI MMDB
Authors
Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
May 05, 2020 
Release Date
May 13, 2020 

Annotation

Ligands

Ligand code Name Ligand type
CL crystallization
SAM s-adenosylmethionine biological
GTA p1-7-methylguanosine-p3-adenosine-5',5'-triphosphate biological
MGP 7-methyl-guanosine-5'-triphosphate biological
ADE adenine biological
SO4 crystallization
ZN biological

Structure information

Unit cell parameters

Space Group
P 31 2 1  
Unit Cell

a=169.37Å, b=169.37Å, c=52.08Å
α=90.00, β=90.00, γ=120.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
29.35-2.00Å (2.05-2.00Å)  
Rall(%)
16.3 
Rwork(%)
16.2 (24.9) 
Rfree(%)
17.8 (25.1) 
Num. observed reflections
57854 (4221) 
Num. Rfree reflections
2892 (185) 
Completeness(%)
99.8 (100.0) 

Model parameters

Num Atoms
3366  
Num Waters
324  
Num Hetatoms
540  
Model mean isotropic B factor
46.880Å2  
RMSD bond length
0.004Å  
RMSD bond angle
1.194°  
Filename uploaded
6wvn.pdb (uploaded on May 30, 2020 11:16 AM)  
Inserted
May 30, 2020