Structure of CPX_52010_52016

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1) and S-Adenosyl-L-homocysteine (SAH).

Edit deposit information
CSGID target
CPX_52010_52016 
PDB Id
7JZ0 (NCBI MMDB
Authors
Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
Sep 01, 2020 
Release Date
Sep 16, 2020 

Annotation

Ligands

Ligand code Name Ligand type
M7G 7n-methyl-8-hydroguanosine-5'-diphosphate biological
A2M 2'-o-methyl-adenosine-5'-monophosphate biological
SAH biological
NA crystallization
CL crystallization
FMT crystallization
ZN biological
U unknown biological
A unknown biological

Structure information

Unit cell parameters

Space Group
P 32 2 1  
Unit Cell

a=167.24Å, b=167.24Å, c=98.87Å
α=90.00, β=90.00, γ=120.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
30.00-2.15Å (2.21-2.15Å)  
Rall(%)
17.5 
Rwork(%)
17.3 (27.1) 
Rfree(%)
19.8 (28.4) 
Num. observed reflections
86137 (6240) 
Num. Rfree reflections
4306 (313) 
Completeness(%)
99.8 (99.1) 

Model parameters

Num Atoms
6712  
Num Waters
393  
Num Hetatoms
593  
Model mean isotropic B factor
55.880Å2  
RMSD bond length
0.005Å  
RMSD bond angle
1.344°  
Filename uploaded
7jz0-PDB.pdb (uploaded on Sep 21, 2020 5:00 PM)  
Inserted
Sep 21, 2020