Structure of CPX_52010_52016

Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA)pUpUpApApA (Cap-0) and S-Adenosylmethionine (SAM).

Edit deposit information
CSGID target
CPX_52010_52016 
PDB Id
7JYY (NCBI MMDB
Authors
Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
Sep 01, 2020 
Release Date
Sep 16, 2020 

Annotation

Ligands

Ligand code Name Ligand type
M7G 7n-methyl-8-hydroguanosine-5'-diphosphate biological
SAM s-adenosylmethionine biological
MG magnesium biological
NA crystallization
CL chloride crystallization
FMT formate crystallization
ZN zinc biological
A unknown biological
U unknown biological

Structure information

Unit cell parameters

Space Group
P 32 2 1  
Unit Cell

a=166.95Å, b=166.95Å, c=98.81Å
α=90.00, β=90.00, γ=120.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
29.97-2.05Å (2.10-2.05Å)  
Rall(%)
16.7 
Rwork(%)
16.6 (24.7) 
Rfree(%)
18.5 (26.9) 
Num. observed reflections
99192 (7228) 
Num. Rfree reflections
5058 (378) 
Completeness(%)
99.9 (99.3) 

Model parameters

Num Atoms
6824  
Num Waters
520  
Num Hetatoms
688  
Model mean isotropic B factor
47.340Å2  
RMSD bond length
0.004Å  
RMSD bond angle
1.290°  
Filename uploaded
7jyy-PDB.pdb (uploaded on Sep 21, 2020 5:06 PM)  
Inserted
Sep 21, 2020