Structure of CPX_52010_52016
Crystal Structure of SARS-CoV-2 Nsp16/10 Heterodimer in Complex with (m7GpppA2m)pUpUpApApA (Cap-1), S-Adenosyl-L-homocysteine (SAH) and Manganese (Mn).
Edit deposit information
- CSGID target
- CPX_52010_52016
- PDB Id
- 7L6R (NCBI MMDB)
- Authors
- Minasov, G., Shuvalova, L., Rosas-Lemus, M., Kiryukhina, O., Brunzelle, J.S., Satchell, K.J.F., Center for Structural Genomics of Infectious Diseases (CSGID).
- Responsible person
- George Minasov
- Responsible lab
- Northwestern University
- Deposition Date
- Dec 23, 2020
- Release Date
- Jan 06, 2021
Annotation
Ligands
| Ligand code | Name | Ligand type |
|---|---|---|
| M7G | 7n-methyl-8-hydroguanosine-5'-diphosphate | biological |
| A2M | 2'-o-methyl-adenosine-5'-monophosphate | biological |
| MN | biological | |
| CL | chloride | crystallization |
| SO4 | sulfate | crystallization |
| SAH | modified residue | |
| GLC | crystallization | |
| ZN | zinc | biological |
| BDF | beta-d-fructopyranose | crystallization |
| U | unknown | biological |
| A | unknown | biological |
Structure information
Unit cell parameters
- Space Group
- P 31 2 1
- Unit Cell
-
a=168.76Å, b=168.76Å, c=52.27Å
α=90.00, β=90.00, γ=120.00 - Solvent content
- Matthews coefficient
- Resolution range
- 29.95-1.98Å (2.03-1.98Å)
- Rall(%)
- 15.1
- Rwork(%)
- 15.0 (27.8)
- Rfree(%)
- 16.6 (25.8)
- Num. observed reflections
- 59437 (4345)
- Num. Rfree reflections
- 3090 (211)
- Completeness(%)
- 99.9 (99.2)
- Num Atoms
- 3368
- Num Waters
- 341
- Num Hetatoms
- 505
- Model mean isotropic B factor
- 43.990Å2
- RMSD bond length
- 0.005Å
- RMSD bond angle
- 1.272°
- Filename uploaded
- 7l6r.pdb (uploaded on Jan 11, 2021 2:40 PM)
- Inserted
- Jan 11, 2021