(*) Hover the mouse over the Substance number to see a preview of the ZINC link.
Rank |
SMILES |
Substance |
|---|---|---|
|
1
|
COC(=O)Cc1nnn(n1)Cc2nnnn2c3ccccc3
|
|
|
2
|
c1ccc(cc1)c2nc(on2)c3c(c4ccccc4s3)O
|
|
|
3
|
Cc1ccnc(c1)Nc2ccc(nn2)NCCNC(=O)C
|
|
|
4
|
CC[C@@H](c1cnn(c1)C)NC(=O)c2c(ocn2)C
|
|
|
5
|
COc1ccc(cc1)n2c3ccccc3nc2Cn4cnc(n4)C#N
|
|
|
6
|
Cc1cc(on1)CCCOc2ccc(cn2)C#N
|
|
|
7
|
CCc1nnc(s1)Nc2ccn(n2)Cc3ccccc3Cl
|
|
|
8
|
c1ccc(cc1)OC(=O)Nc2csc(n2)Cc3ccsc3
|
|
|
9
|
C1CCC(CC1)S(=O)(=O)NCCN2CCNC2
|
|
|
10
|
|
|
|
11
|
c1ccnc(c1)SCc2ncn(n2)c3cccc(n3)F
|
|
|
12
|
c1ccc(cc1)[C@@H]2CC=N[C@@H](N2)Nc3nc4ccccc4o3
|
|
|
13
|
CCc1nnc(s1)NC(=O)c2c(ocn2)c3cccs3
|
|
|
14
|
Cc1ccc(cc1C)Oc2cc(nc(n2)SC)n3cncn3
|
|
|
15
|
c1ccc(cc1)NC(=O)NC23CC4CC(C2)CC(C4)C3
|
|
|
16
|
CN1C(NCN1)CCC2CCCCC2
|
|
|
17
|
c1ccc(cc1)c2nnnn2SCC(=O)c3ccccc3
|
|
|
18
|
CC(=O)O[C@@H](c1ccccc1)C(=O)Nn2c(nnn2)N
|
|
|
19
|
CC[C@@H]1COC(=N1)COCC2CCCCC2
|
|
|
20
|
Cc1nc(c(o1)NCCc2nc(no2)c3ccccc3)C#N
|
|
|
21
|
Cnccs/c1=NC(=O)CNS(=O)(=O)c2cnn(c2)C
|
|
|
22
|
c1ccc(cc1)c2csc(n2)n3cccn3
|
|
|
23
|
Cc1ccc(cc1)S(=O)(=O)NC[C@@]23CC(=O)C[C@@H](O2)C=C3
|
|
|
24
|
c1ccc(cc1)[C@@]2(CCN(C2)Cc3ccnn3[C@@H]4CCCCO4)O
|
|
|
25
|
CCc1c(ccc(n1)C)OCc2[nH]c3cnccc3[nH+]2
|
|
|
26
|
CCN(CCc1nc(nc(n1)N)N)c2ccccc2
|
|
|
27
|
CNC(=O)c1c2c(ccs2)nc(n1)NCc3cccnc3
|
|
|
28
|
Cc1ncc(c(n1)N)CSc2nc(ns2)SC
|
|
|
29
|
CCC1NC(ON1)COC(=O)C2CC[NH]N2
|
|
|
30
|
Cc1ccccc1CN[C@@H]2COC[C@H]2c3ccc(cc3)F
|
|
|
31
|
CCOC(=O)Nc1cc2c(c(n1)N)N=C(CO2)c3ccccc3
|
|
|
32
|
c1ccc2c(c1)CN(CCN2)c3cnc4ccccc4n3
|
|
|
33
|
Cc1c(non1)NC(=O)OC[C@@H]2CCCO2
|
|
|
34
|
c1cnc([nH]1)Cc2[nH]c(cn2)Cc3cnc[nH]3
|
|
|
35
|
CCn1cnnc1c2cc(c[nH]2)C(=O)c3ccccc3O
|
|
|
36
|
c1ccc(cc1)c2nc(co2)COc3cn(nn3)c4ccccc4
|
|
|
37
|
Cc1cc(nc(n1)C)n2cnc(n2)C#N
|
|
|
38
|
Cc1cccc(n1)c2nnc(o2)c3csc(n3)N4CCOCC4
|
|
|
39
|
Cc1ccc(cc1)c2nc(on2)c3cc4ccccc4[nH]3
|
|
|
40
|
c1ccc(cc1)n2nc3ccc4c(c3n2)nc(cn4)N
|
|
|
41
|
c1ccc(cc1)[C@@H](CSc2nc-3n(n2)CNc4c3cccc4)O
|
|
|
42
|
c1ccc2c(c1)c(c[nH]2)Cn3cnnc3
|
|
|
43
|
CC1C(C(NC(N1)C)CC2C3CCCCC3NCN2)CL
|
|
|
44
|
c1ccc(cc1)C(=O)OC[C@@H]2COC(=O)N2
|
|
|
45
|
|
|
|
46
|
c1ccc(cc1)c2cs/c(=N/C(=O)c3ccc(cc3)F)/o2
|
|
|
47
|
Cc1nc([nH]n1)CNC(=O)Nc2[nH]nc(n2)Cc3ccccc3
|
|
|
48
|
Cc1cc(nc(n1)n2cc(nn2)C(=O)c3ccccn3)C
|
|
|
49
|
c1ccc(cc1)Cn2cnc(n2)NC3=Nc4cccc5c4c3ccc5
|
|
|
50
|
Cc1nc(on1)NC(=O)C[C@@H]2CCC=C2
|
|
|
51
|
C[C@@H](c1ccc(nn1)Cl)NC(=O)OCc2ccccc2
|
|
|
52
|
c1cc2n(c1)CCN(C2)/C(=N/c3[nH]nc(n3)c4ccco4)/[O-]
|
|
|
53
|
Cc1nc(on1)C(=O)NCc2ccco2
|
|
|
54
|
c1cc(cnc1)Cc2cnc[nH]2
|
|
|
55
|
Cc1nnc(s1)Sc2cnc3ccccc3n2
|
|
|
56
|
Cc1nnc(o1)CNC(=O)C2CCC2
|
|
|
57
|
|
|
|
58
|
CCO[C@@H](C)C(=O)/N=c/1[nH]c(n[nH]1)c2ccc(s2)C
|
|
|
59
|
CS(=O)(=O)NCc1ccccn1
|
|
|
60
|
c1ccc(c(c1)C(=O)c2cc([nH]c2)c3ccccn3)O
|
|
|
61
|
Cc1c(non1)CC(=O)NCC[C@@H]2C[C@H]3C[C@@H]2C=C3
|
|
|
62
|
c1cc(cnc1)c2cc([nH]n2)N
|
|
|
63
|
Cc1c(nc2ccccc2n1)OCc3nc(no3)C4CC4
|
|
|
64
|
|
|
|
65
|
c1cc(cnc1)CCNCc2cscn2
|
|
|
66
|
Cc1nnc(s1)SCSc2ccccn2
|
|
|
67
|
c1ccc(cc1)NCCn2cccc2
|
|
|
68
|
CCCc1c(c(n(n1)C)[O-])C(=O)c2cc3ccccc3s2
|
|
|
69
|
Cc1[nH]c(=O)cc(n1)Cn2cnc3c2cccc3
|
|
|
70
|
Cc1ccc(cc1)/N=C/Cc2c(nnc(n2)SCC=C)C
|
|
|
71
|
c1ccc2c(c1)[nH]c(n2)Sc3ccc(o3)CO
|
|
|
72
|
c1ccc(cc1)NC(=O)C[C@@H]2C(=O)NC(=[NH+]2)N3CCCCC3
|
|
|
73
|
C1CCC(CC1)/C=C/CN2CCNC2C3CNCCN3
|
|
|
74
|
c1ccc(cc1)Nc2nc(nc(n2)N)Cc3cc(n[nH]3)O
|
|
|
75
|
COc1ccnc(n1)Sc2[nH]cc(n2)c3ccccc3
|
|
|
76
|
Cc1cnn(c1)c2cc(ncn2)c3cccnc3
|
|
|
77
|
c1cc(cnc1)Nc2nsc(=O)n2c3cccnc3
|
|
|
78
|
c1ccc(cc1)COC(=O)Nc2ccc3c(c2)CCCC=C3
|
|
|
79
|
c1cc(cnc1)[C@@H]2Nc3c(nc[nH]3)C(=O)N2
|
|
|
80
|
C1CCC(CC1)C2=CC(=C(C2)C(=O)[O-])C3CCCCC3
|
|
|
81
|
CSc1nc(cc(n1)Cl)[C@@H](C#N)c2cc3ccccc3cn2
|
|
|
82
|
c1ccc2c(c1)nc(o2)n3cnc(n3)C#N
|
|
|
83
|
Cc1c(c(on1)C)c2nc(no2)CN3CCOCC3
|
|
|
84
|
Cc1cc(no1)/N=C/Cc2nnnn2c3ccccc3
|
|
|
85
|
c1cocc1C(=O)OCc2nc(nc(n2)N)N
|
|
|
86
|
Cc1cc(n(n1)NC(=O)CCc2ccccc2)C
|
|
|
87
|
Cc1csc(n1)c2cc(c[nH]2)C(=O)c3ccccc3O
|
|
|
88
|
Cc1ccc(c(c1C)O)c2cc(n[nH]2)C(=O)NCc3ccncc3
|
|
|
89
|
c1ccc2c(c1)[nH]c(=NC(=O)CSc3nncs3)[nH]2
|
|
|
90
|
c1cc(ccc1C2=NC(=CC2)c3ccncc3)Cl
|
|
|
91
|
CCc1nc(cs1)CNCc2nc(no2)C
|
|
|
92
|
c1ccc(cc1)C(=O)Cc2c([nH]nc2N)N
|
|
|
93
|
c1ccc2c(c1)c(cs2)Nc3cccnc3
|
|
|
94
|
C=Cn1ccnc1CCOC(=O)c2ccc(cc2)Cl
|
|
|
95
|
CCCOCC(=O)/N=c/1[nH]c(n[nH]1)c2ccccn2
|
|
|
96
|
c1cc(ccc1c2c(c[nH]n2)N3C=CCCC3=O)Cl
|
|
|
97
|
c1ccnc(c1)c2cc([nH]n2)C(=O)NCCn3cncn3
|
|
|
98
|
c1ccc(cc1)C#CC(=O)c2cccs2
|
|
|
99
|
c1cc(cc(c1)F)n2ccc(n2)Cn3cnc(n3)C#N
|
|
|
100
|
C1CCC(CC1)[C@@H]2CC/C(=C/3C=CC(=N3)C4CCCCC4)/[NH2+]2
|
|
|
101
|
Cc1cc(nc(n1)SC)C(=O)Nc2c(nsc2C)C
|
|
|
102
|
CCc1nc(c(o1)C(=O)NCCSc2[nH]ncn2)C
|
|
|
103
|
Cc1cc(nc(n1)Sc2nc(nc(n2)Cl)NC)C
|
|
|
104
|
c1cc(ccc1SCCCn2ccnc2)Cl
|
|
|
105
|
c1ccc(cc1)c2c(nc([nH]2)c3ccco3)N
|
|
|
106
|
CN(C/C(=N/c1[nH]ncn1)/[O-])c2ccccc2
|
|
|
107
|
c1ccc(cc1)NC(=O)OCc2cncs2
|
|
|
108
|
c1cc(oc1)C(=O)NC/C(=N/c2[nH]ncn2)/[O-]
|
|
|
109
|
c1ccc2c(c1)CC[C@@H](C(=N2)O)Sc3[nH]ncn3
|
|
|
110
|
Cc1nc(on1)[C@@H](C)Nc2ccc(nc2)OC
|
|
|
111
|
Cc1cnn(c1)CC/C(=N/c2[nH]ncn2)/[O-]
|
|
|
112
|
c1ccc(cc1)Nc2c(nnn2c3ccccc3)c4ccn[nH]4
|
|
|
113
|
c1ccc(c(c1)C(=O)c2cc([nH]c2)c3nc(no3)C4CC4)O
|
|
|
114
|
c1ccc2c(c1)nc(s2)CSc3[nH]ncn3
|
|
|
115
|
CCOC(=O)C=NN=C/C1=N/NSC2CCC(CC2)C
|
|
|
116
|
Cc1cc(n(n1)c2nc3ccccc3o2)N
|
|
|
117
|
c1ccc2c(c1)nnn2CCS(=O)(=O)N3CCCC3
|
|
|
118
|
CCn1cc(cn1)c2cncn2CCCC(C)(C)CO
|
|
|
119
|
CN1CNNC1CNC2CNC3CCCCC3N2
|
|
|
120
|
Cc1c2c(oc(c2c(=O)[nH]n1)NC(=O)Cn3ccnc3)C
|
|
|
121
|
c1ccc(cc1)C(=O)NCn2cncn2
|
|
|
122
|
CCn1c2ccccc2nc1c3cnn(n3)c4ccccc4
|
|
|
123
|
c1ccc(cc1)SC/C(=N/c2[nH]ncn2)/[O-]
|
|
|
124
|
Cc1c(c2cc(ccc2[nH]1)F)CCn3cnnn3
|
|
|
125
|
Cc1nnc(s1)SCn2c3ccccc3nn2
|
|
|
126
|
CN(Cc1ccc(cc1)C#N)Cc2nc(nc(n2)N)N
|
|
|
127
|
c1ccc2c(c1)[nH]c(=NC(=O)c3ccc[nH]3)[nH]2
|
|
|
128
|
Cc1cc(ccc1/N=C/Cc2cccs2)OCC(=O)[O-]
|
|
|
129
|
c1ccc2c(c1)CC3=C2NC(=O)N[C@@H]3c4ccccn4
|
|
|
130
|
c1cc(cnc1)c2nnc(s2)Cc3cccs3
|
|
|
131
|
c1ccc(cc1)n2c(nnn2)Sc3nc4ccccc4o3
|
|
|
132
|
COC(=O)CN1CNC(N1)C2[NH]C(=O)C3C(N2)CCS3
|
|
|
133
|
c1ccc(cc1)n2c(cnn2)Cn3cnc4ccccc4c3=O
|
|
|
134
|
CC(C)(C)c1csc(n1)c2ccc(nc2)n3cncn3
|
|
|
135
|
Cc1cc(cc(c1)NC(=O)c2c(nco2)C)C
|
|
|
136
|
Cc1ccc(cc1)NC(=O)COc2cn(nn2)c3ccccc3
|
|
|
137
|
c1ccc2c(c1)c(c[nH]2)c3c[nH]c(n3)C(=O)c4c[nH]c5c4cccc5
|
|
|
138
|
c1cc(oc1)/C=C/CNc2ccc(c(c2)Cl)F
|
|
|
139
|
CCc1nnc(o1)Cn2cnc3ccccc3c2=O
|
|
|
140
|
Cc1cc(nc(n1)c2csc(n2)C)NC
|
|
|
141
|
|
|
|
142
|
C[C@@H](c1ccnc(n1)N)Oc2ncn(n2)c3ccccc3
|
|
|
143
|
CCc1n[n-]/c(=N/C(=O)c2c(c(c(c(c2F)F)F)F)F)/s1
|
|
|
144
|
Cc1c(cn(n1)CC=C)CNCc2c(nns2)C
|
|
|
145
|
Cc1nc(on1)Cc2c[nH]c3c2cccc3
|
|
|
146
|
Cc1ccc(cc1)SC(=O)N/C=C/c2ccsc2
|
|
|
147
|
Cc1ccc(cc1)S(=O)(=O)NC(=O)n2c(cc(n2)C)C
|
|
|
148
|
Cn1c(nnc1SCC=C)Cn2cnc3c2cccc3
|
|
|
149
|
c1nc(nn1CCN2CCOC2=O)C#N
|
|
|
150
|
CC(C)(C)OC(=O)NCCc1nc2cnccc2o1
|
|
|
151
|
Cc1c(c(c([nH]1)C)C(=O)OC)c2cc[nH]n2
|
|
|
152
|
Cc1nc([nH]n1)/N=C(/N(C)Cc2ccco2)[O-]
|
|
|
153
|
CCOC(=O)c1cnc(nc1Sc2nnc(s2)C)SC
|
|
|
154
|
c1ccc2c(c1)c(=O)n(nn2)Cn3cnc(n3)C#N
|
|
|
155
|
CC1=C[C@@H](c2c1nc3ccccc3n2)c4cnc5ccccc5n4
|
|
|
156
|
c1ccc(cc1)[C@@H]2NC(=[NH+]C(=N2)c3ccccc3)c4ccccc4
|
|
|
157
|
c1cscc1C(=O)c2cn[nH]c2N
|
|
|
158
|
c1ccc(cc1)CCc2cc(=O)cc([nH]2)c3ccccc3
|
|
|
159
|
Cc1nnc(o1)C(=O)c2c(c3ccccc3n(c2=O)C)OC(=O)C
|
|
|
160
|
c1ccc2c(c1)C[C@@H](CO2)/C(=N/c3[nH]ncn3)/[O-]
|
|
|
161
|
c1ccc(cc1)c2nnn(n2)CCS(=O)(=O)N3CCOCC3
|
|
|
162
|
c1ccc2c(c1)[nH]c(n2)Nc3nc(nc(n3)[O-])CC#N
|
|
|
163
|
CSc1nc(cc(n1)n2cnc3c2cccc3)c4ccccc4
|
|
|
164
|
Cc1ccc(cc1)S(=O)(=O)Oc2nc(cc(n2)C)C
|
|
|
165
|
C[C@@H]1CCCC[C@@H]1NC(=O)COc2cnc(nc2)c3ccccc3
|
|
|
166
|
c1cc(cnc1)[C@@]2(CCC=C2)O
|
|
|
167
|
c1ccc(cc1)[C@@H]2NC(=[NH2+])Nc3n2c4ccccc4n3
|
|
|
168
|
c1cc(ccc1NC(=O)Cc2ncon2)F
|
|
|
169
|
|
|
|
170
|
c1ccc2c(c1)C(=O)c3cccc4c3C2=NNS4(=O)=O
|
|
|
171
|
c1cc(nn2c1nnn2)n3cnc(n3)C#N
|
|
|
172
|
CC(C)(C)OC(=O)NCCn1c(c(nn1)C#N)N
|
|
|
173
|
Cc1c(non1)NC(=O)OCCN2CCOC2=O
|
|
|
174
|
Cn1nc(nn1)[C@@H](CNCc2cccs2)O
|
|
|
175
|
CC[C@@H](c1nc(no1)C)NCc2cn(nc2C)CC=C
|
|
|
176
|
Cc1nc(cn1Cc2ccc(cc2)F)c3ccc4ccccc4n3
|
|
|
177
|
c1cc(ccc1OC(=O)NCn2ccnc2)Cl
|
|
|
178
|
Cc1c(c(c(o1)C)C(=O)[O-])c2ccc3c(c2)[nH]/c(=NC(=O)OC)/[nH]3
|
|
|
179
|
Cc1nc(on1)S[C@@H](C)c2nc(nc(n2)N(C)C)N
|
|
|
180
|
c1ccc2c(c1)nc(o2)Nc3nc4ccccc4s3
|
|
|
181
|
CCOC(=O)c1c(cc([nH]1)c2ccco2)N
|
|
|
182
|
c1ccc2c(c1)cnn(c2=O)Cc3nnnn3C4CC4
|
|
|
183
|
CC1C(OC(N1)NC(=O)N(C)C2CC2)C
|
|
|
184
|
C1CCC(CC1)C2C(C(=O)C2=O)/C=C/NC3CCCCC3
|
|
|
185
|
Cn1c(cc(n1)C(=O)OC)OC(=O)c2ccco2
|
|
|
186
|
c1ccc2c(c1)[nH]c(n2)C/C=N/c3nccs3
|
|
|
187
|
c1ncn(n1)Cc2nc([nH]n2)CC#N
|
|
|
188
|
Cc1cc(nc(n1)SNc2ccccc2OC)C
|
|
|
189
|
|
|
|
190
|
c1ccc2c(c1)CC[C@@]3(C2)Nc4ccccc4S3
|
|
|
191
|
CCCSc1ncc(cn1)CN[C@@H](CC)c2ncnn2C
|
|
|
192
|
COCCN1CNC(=NC1)Nc2nc3ccccc3o2
|
|
|
193
|
CCOC(=O)/C=C(/c1cnc2n1cccc2)C(F)(F)F
|
|
|
194
|
c1cc(cnc1)[C@@H]2NC(CO2)(CO)CO
|
|
|
195
|
c1ccc(cc1)c2nnc(o2)Cn3cncn3
|
|
|
196
|
Cn1ccnc1SCC(=O)C(=C2Nc3ccccc3N2)C#N
|
|
|
197
|
CS(=O)(=O)N1CCCN(CC1)Cc2nnnn2C3CC3
|
|
|
198
|
CC(=C)[C@@H](C(=O)OC)N1C(=O)C(CS1)NCC2CCCCC2
|
|
|
199
|
c1ccc(cc1)NC(=O)CSc2ccc(o2)c3ccncc3
|
|
|
200
|
CCN1CC(=O)N=C1NCCc2cccc(c2)Cl
|
|
|
201
|
c1ccc(cc1)n2cnnc2CC(=O)c3ccc(cc3O)O
|
|
|
202
|
C[C@@H](c1ccco1)/N=c/2ccccn2C(=O)Nc3ccccc3
|
|
|
203
|
CCOc1ccc(cc1)NCC2=CCNC=C2
|
|
|
204
|
CC1=C(N/C(=C/2C=CC=CC2=O)/N1)c3ccccc3
|
|
|
205
|
CCc1ccc(cc1)S(=O)(=O)[N-]c2nc(ns2)SC
|
|
|
206
|
Cc1c(oc(n1)NS(=O)(=O)c2ccc(cc2)N)C
|
|
|
207
|
c1ccnc(c1)c2cn(nn2)C3CCN(CC3)C(=O)C4CC4
|
|
|
208
|
c1ccc2c(c1)ncn2Cc3nnc(o3)N
|
|
|
209
|
c1ccc2c(c1)nc(s2)n3cnc(n3)C#N
|
|
|
210
|
CCN1CNC(=NC1)Nc2nc(c3ccccc3n2)C
|
|
|
211
|
Cc1c(n(c(=O)n1c2ccccc2)C)NC(=O)NC3CCCC3
|
|
|
212
|
Cc1ccc(cc1)c2nnc(o2)c3c(cnc(n3)SC)Cl
|
|
|
213
|
CCS(=O)(=O)NCc1nnc(o1)C
|
|
|
214
|
Cn1c(=O)c(c(cn1)Cl)[C@@H](C#N)c2nc3ccccc3s2
|
|
|
215
|
c1ccc(cc1)S(=O)(=O)CCn2cnc(n2)C#N
|
|
|
216
|
c1cc(cnc1)N2CC[C@H]3C[NH2+][C@H]3C2
|
|
|
217
|
c1ccnc(c1)n[nH]/c2=NC(=O)COCC3CC3
|
|
|
218
|
c1ccc(cc1)S(=O)(=O)NCc2nccs2
|
|
|
219
|
c1ccc2c(c1)nnn2CNC(=O)c3ccco3
|
|
|
220
|
Cc1cnc(o1)CN(C)Cc2ccco2
|
|
|
221
|
c1ccc(cc1)c2cc(c3nnnn3c2)CNc4cccnc4
|
|
|
222
|
C[C@@H](c1ccn[nH]1)Oc2ccccc2
|
|
|
223
|
Cc1nnc(o1)COC(=O)c2c(nccn2)N
|
|
|
224
|
c1cnc(nc1)N2CCC[C@@H](C2)Cn3cc(nn3)CO
|
|
|
225
|
Cc1nc(on1)NC(=O)CSc2nncn2C3CC3
|
|
|
226
|
CC(C)(C)OC(=O)[C@@H]1CN(C(=O)N1)C
|
|
|
227
|
Cc1c(oc(n1)SCc2nc(nc(n2)N)N)C
|
|
|
228
|
Cc1c(non1)NS(=O)(=O)c2ccccc2
|
|
|
229
|
c1ccc2c(c1)nc(s2)Cn3cnc(n3)C#N
|
|
|
230
|
CS(=O)(=O)NC1=NCN(CN1)Cc2ccccn2
|
|
|
231
|
CC1C(CNO1)/C=C/C2CCON2
|
|
|
232
|
Cc1cc(nc2c1nc(o2)OCc3ccc(cc3)Cl)C
|
|
|
233
|
Cc1ccc(nn1)NCCSc2nccn2C
|
|
|
234
|
c1ccc2c(c1)-c3ccccc3C24CNC(=O)O4
|
|
|
235
|
c1ccc2c(c1)ccn2Cc3nnc(s3)Cc4cccs4
|
|
|
236
|
c1cc(cc(c1)N/C=c/2ccc3c4c2cccc4c(=O)n3)C(=O)[O-]
|
|
|
237
|
CSc1c(c(sn1)SC)NC(=O)OC[C@@H]2CCCO2
|
|
|
238
|
c1cc(cnc1)n2c3c(ccc4c3cn[nH]4)c(n2)C(=O)N
|
|
|
239
|
Cc1nc(nn1C)NC(=O)NCc2ccon2
|
|
|
240
|
Cc1nnc(s1)SC2=C(Nc3ccccc3NC2=O)C
|
|
|
241
|
|
|
|
242
|
c1ccc2c(c1)CC[NH+]=C(N2)N3CCOCC3
|
|
|
243
|
Cc1c(c2c(=O)[nH]cnc2s1)S(=O)(=O)N3CCCCC3
|
|
|
244
|
COCCCNC(=O)c1c(=O)c2ccccc2sc1N
|
|
|
245
|
Cc1nc(no1)Cn2c(=O)n(nn2)c3ccccc3
|
|
|
246
|
c1ccc2c(c1)[nH]c(n2)NC3=NC(=O)C(=N3)[O-]
|
|
|
247
|
COc1ccc2c(c1)C=C(CO2)CNc3cccnc3
|
|
|
248
|
CC(C)c1c[nH]c(n1)COCc2ccccc2
|
|
|
249
|
c1cc(cc(c1)Cl)n2ccc(n2)c3cnccn3
|
|
|
250
|
c1cc(ccc1c2c(n[nH]n2)Nc3c(non3)N)Cl
|
|
|
251
|
CC1=NC(=O)C2(N1)CCN(CC2)c3ccnc4c3cn[nH]4
|
|
|
252
|
c1ccc(cc1)/C=C/c2cc([nH]n2)CCc3[nH]c4ccccc4n3
|
|
|
253
|
c1ccn2cc(nc2c1)Cn3cc(cn3)N
|
|
|
254
|
CCOC(=O)CCc1cn2cc(nc(c2n1)OC)Br
|
|
|
255
|
CCOC(=O)C1CC(CN1C)N2C3CCCCC3NN2
|
|
|
256
|
Cc1cc(nc(n1)n2c(cc(n2)c3ccco3)N)C
|
|
|
257
|
Cn1cc(nc1)S(=O)(=O)Oc2ccsc2C(=O)OC
|
|
|
258
|
c1ccc(cc1)Nc2nc(nc(n2)N)CN3CCC[C@@H]3C(=O)N
|
|
|
259
|
Cn1ncc(n1)NC(=O)CCc2cn3ccccc3n2
|
|
|
260
|
CCc1cc(c(=O)[nH]c1C)CCC2=N[C@@H]3CCCC[C@@H]3O2
|
|
|
261
|
c1cc(oc1)c2nn(c(=O)o2)CCC#N
|
|
|
262
|
c1ccc2c(c1)[nH]c(=O)n2c3csc(n3)c4ccncc4
|
|
|
263
|
CC(C)[C@@H](NC(=O)OCc1ccccc1)n2cncn2
|
|
|
264
|
c1cc(cnc1)C2=NC(=O)[C@@H](C=C2)C#N
|
|
|
265
|
c1cnccc1c2cc3c([nH]2)CNC3=O
|
|
|
266
|
c1ccc2c(c1)c(ns2)SCn3c4ccccc4nn3
|
|
|
267
|
CC1(CC2=C[C@@H]3C[C@]2([C@@H]4[C@@H]3CC5=C4CC(OC5=O)(C)C)C(=O)O1)C
|
|
|
268
|
Cc1nnc(o1)NCc2nc(cs2)c3ccc(cc3)F
|
|
|
269
|
c1ccnc(c1)SCCn2cccn2
|
|
|
270
|
Cc1nc(on1)/C=C/c2ccccc2O
|
|
|
271
|
c1ccc(c(c1)N)NCCCn2ccnc2
|
|
|
272
|
c1cc(oc1)CNC(=O)CSc2[nH]ncn2
|
|
|
273
|
CCc1nc([nH]n1)Sc2cnc3ccccc3n2
|
|
|
274
|
C1CCC(CC1)/C=C/N2CCNC2
|
|
|
275
|
c1ccc(cc1)C(=O)/C=C/C(=O)Nc3c(cccn3)N2
|
|
|
276
|
COC(=O)CCCCc1c2c(cs1)[nH]c(=O)[nH]2
|
|
|
277
|
c1ccc(cc1)c2nc(on2)c3c(=O)ccn(n3)c4ccccc4
|
|
|
278
|
c1cc2cccc3c2c(c1)c(=C(C#N)C#N)[nH]3
|
|
|
279
|
c1c(nc2n1CCS2)CNC(=O)[C@@H]3CC(=O)OC34CCCC4
|
|
|
280
|
CCc1nc([nH]n1)Sc2nc3ccccc3o2
|
|
|
281
|
c1ccc(cc1)[C@@H]2C[C@@H](n3c(cnn3)N2)c4ccco4
|
|
|
282
|
c1ccc2c(c1)C=Nc3c(ncnc3O2)N4CCOCC4
|
|
|
283
|
c1ccc(cc1)c2c(=O)cc3n(n2)c(=O)c4ccccc4s3
|
|
|
284
|
Cc1c(c(on1)C)C/C(=N/c2[nH]ncn2)/[O-]
|
|
|
285
|
Cn1cncc1COC(=O)c2ccc(cc2)Cl
|
|
|
286
|
c1ccc-2c(c1)CNC(=O)c3c2cccc3
|
|
|
287
|
c1cnc(c(n1)C#N)NCc2nc3c(s2)CCCC3
|
|
|
288
|
c1cnccc1c2cc3n(n2)CCNC3=O
|
|
|
289
|
c1ccc2c(c1)c(c[nH]2)Cc3c[nH]c4c3CCC=C4
|
|
|
290
|
c1ccnc(c1)n[nH]/c2=NC(=O)C3CC3
|
|
|
291
|
c1ccc2c(c1)-c3c[nH]c4c3c(ccc4)C2=O
|
|
|
292
|
Cc1cc(ncn1)SCc2csc(n2)C
|
|
|
293
|
CC(C)(C)OC(=O)NCc1[nH]nc(n1)c2ccccc2
|
|
|
294
|
CCO[C@@H](C#Cc1ccccc1)n2cncn2
|
|
|
295
|
c1ccc2c(c1)nnn2Cn3cccc3
|
|
|
296
|
Cc1cccc(n1)C#CCNc2ccccc2
|
|
|
297
|
c1ccc2c(c1)c(=O)n(cn2)Cc3c(snn3)Cl
|
|
|
298
|
c1ccc2c(c1)N=CC=C(S2)c3cccnc3
|
|
|
299
|
c1cc([nH]c1)c2nnc(o2)Sc3ccc(cn3)C#N
|
|
|
300
|
CC1(OC(=O)C(C(=O)O1)CN/C=C/C2=CCCCC2)C
|
|
|
301
|
CC(=O)c1ncc(o1)c2ccccn2
|
|
|
302
|
c1ccc2c(c1)c-3c4c(nc(=[NH2+])c3c(o2)O)CCCCC4
|
|
|
303
|
CC1(COC(=N1)/C=C/c2ccccc2)C
|
|
|
304
|
Cn1cc(cn1)NCc2ccc[nH]2
|
|
|
305
|
CCOC(=O)c1c(c(cn1C)NC(=O)OCc2ccccc2)O
|
|
|
306
|
CC(=O)c1ccc(cc1)Oc2nc(on2)c3ccccc3F
|
|
|
307
|
c1c([nH]cn1)CCNC(=O)C2=NC=NC2
|
|
|
308
|
c1cc2c(cc1/C=C/c3nnc(o3)c4cnccn4)OCCO2
|
|
|
309
|
c1cc2c(cc1C3=CNC(=O)CO3)cc([nH]2)c4ccncc4
|
|
|
310
|
COC1=C(C(=O)O[C@@H]2[C@@H]1C=CC=C2)Cc3ccccc3
|
|
|
311
|
c1ccc(cc1)/C=C/CN2CCC(CC2)C#N
|
|
|
312
|
C/C(=C/C=CC=CCc1cnco1)/[C@H](C(C)(C)C(=O)N)O
|
|
|
313
|
Cc1cc(c(c(c1)C)OS(=O)(=O)Nc2cccnc2)C
|
|
|
314
|
C1CCC(CC1)C2=N[C@@H]2COC(=O)C3CCC(CC3)BR
|
|
|
315
|
Cc1c(n[nH]c(=O)c1C#N)/C=C/c2cccs2
|
|
|
316
|
Cc1ccn(n1)CCNC(=O)c2c(n[nH]n2)c3ccccc3
|
|
|
317
|
Cc1cccc(c1)NC2=CC(=O)[C@H]([NH+]=N2)c3ccccc3
|
|
|
318
|
Cc1cc(nc(n1)Nc2nc(on2)COc3ccccc3)C
|
|
|
319
|
Cc1cc(no1)Cn2cnc3ccccc3c2=O
|
|
|
320
|
Cc1nc(on1)CCCc2c[nH]c3c2cccc3
|
|
|
321
|
C1C2CC3CC1CC(C2)C34C=C(N=C(N4)N)C(F)(F)F
|
|
|
322
|
c1c(cn(n1)Cc2nc(nc(n2)N)N)Cl
|
|
|
323
|
c1cc(cnc1)CNCCc2ccco2
|
|
|
324
|
c1cc(ccc1C#N)C(=O)OCc2nccn2C(F)F
|
|
|
325
|
c1ccc2c(c1)Cc3cnc4ccccc4c3N2
|
|
|
326
|
CC(C)Oc1cccc(c1)C(=O)Oc2nnnn2C
|
|
|
327
|
Cc1c(cnc(n1)C2CC2)c3nc(sn3)Nc4ccccc4
|
|
|
328
|
Cc1cccc(c1)NC(=O)N2C[C@@H]3C[C@H]2C=C3
|
|
|
329
|
CCC(=O)c1cc(c(c(c1)Sc2cccc3c2nccc3)O)C
|
|
|
330
|
Cc1c2c([nH]n1)NC3=C([C@@H]2C)C(=O)OC3
|
|
|
331
|
Cn1c(=O)ccn(c1=O)C/C(=N/c2[nH]ncn2)/[O-]
|
|
|
332
|
c1ccc(cc1)[C@@H]2CC(=C(O2)N)c3nc4ccccc4s3
|
|
|
333
|
Cc1nc(cs1)c2nc(cs2)C(=O)C
|
|
|
334
|
c1ccc(cc1)O[C@@H]2C[C@H]3CC[C@@H]2[C@@H]4[C@@H]3C=C4
|
|
|
335
|
Cc1c2c(nc(n1)n3cc(nn3)c4ccccc4)CCCC2
|
|
|
336
|
Cc1[nH]cc([nH+]1)S(=O)(=O)[N-]c2cc(nn2C)c3ccccc3
|
|
|
337
|
Cc1ccc(o1)Cc2cc(c(o2)C)c3ccccc3
|
|
|
338
|
COC(=O)Cn1c(c([nH]c1=O)/C=C/2C=Nc3c2cccc3)O
|
|
|
339
|
c1cn[nH]c1c2c(n(nn2)C3CCCCC3)NC4CCCCC4
|
|
|
340
|
CCC(=O)Nc1cnn(c1)Cc2nnnn2CCOC
|
|
|
341
|
C[C@@]12CC3C[C@@](C1)(CC(C3)(C2)C(=O)NCCCc4[n-]nnn4)C
|
|
|
342
|
COCCSc1nnc(o1)c2c[nH]c3c2cccc3
|
|
|
343
|
c1ccc(cc1)c2c(c(=O)c3ccccc3[nH]2)C(=O)c4ccccc4
|
|
|
344
|
Cc1ccc(o1)C(=O)Cc2c(=O)oc3ccccc3n2
|
|
|
345
|
Cc1ccc(cc1)C(=O)Cc2nnc(s2)C
|
|
|
346
|
CCSC1[NH]C(=O)C2C(N1)CCN(C2)C3CCCCC3
|
|
|
347
|
c1ccc(cc1)N(CCC#N)c2c(c3ccccc3s2)Cl
|
|
|
348
|
Cc1c(oc(n1)S[C@@H](C)c2cccnc2)C
|
|
|
349
|
c1c2c(n[nH]c1=O)CCCC2
|
|
|
350
|
c1cc2c(c[nH]c2nc1)C3=CCCCC3
|
|
|
351
|
C[S@@](=NCn1c2ccccc2nn1)(=O)c3ccccc3
|
|
|
352
|
CS(=O)(=O)N1CC[C@@H](C1)c2[nH]c3cccnc3n2
|
|
|
353
|
c1ccc(cc1)CNc2ccnc(n2)n3cnc4c3cncc4
|
|
|
354
|
CC(=CCC/C(=C/Cn1ccnc1)/C)C
|
|
|
355
|
C[C@@H]1C(=C(Nc2n1c3ccccc3n2)C)C(=O)OC
|
|
|
356
|
CC(C)(C)OC(=O)NCCc1cn(nn1)Cc2cscn2
|
|
|
357
|
C[C@@]1(C(=Nc2ccccc2O1)O)C(=O)Nc3ccon3
|
|
|
358
|
c1ccc(cc1)C/N=c/c(=N/CCO)/c(c2O)O
|
|
|
359
|
c1ccc(cc1)SCCc2nnc(o2)N
|
|
|
360
|
Cc1cnc(o1)CN2CCc3c2cccc3
|
|
|
361
|
Cc1c(non1)CNS(=O)(=O)CC=C
|
|
|
362
|
C/C(=CCc1cccc(n1)C(=O)N)/CCC(=O)[O-]
|
|
|
363
|
COC(=O)c1cc2c(o1)Sc3ccccc3NC2=O
|
|
|
364
|
c1cc(cnc1)c2[nH]cc([nH+]2)C3CCCCC3
|
|
|
365
|
C[C@@H](N1CCNC1)OCCCC2CCCCC2
|
|
|
366
|
c1ccc(cc1)OCC(=O)Nc2[n-]nnn2
|
|
|
367
|
Cc1c(cn(n1)C(=O)C)c2nc(sn2)Nc3ccccc3
|
|
|
368
|
c1ccc(cc1)n2cc(cn2)CSc3nncs3
|
|
|
369
|
c1ccc(cc1)[C@@H](c2c[nH]nc2)O
|
|
|
370
|
COCC(=O)N1CCC[C@@H](C1)c2c3c([nH]n2)nccn3
|
|
|
371
|
Cc1nnc(n1c2ccc(cc2)OC)Sc3ccccn3
|
|
|
372
|
CN(Cc1c(snn1)Cl)S(=O)(=O)c2ccc(cc2)F
|
|
|
373
|
CN(CCc1ccccn1)c2nc(=[N+](C)C)ss2
|
|
|
374
|
c1ccc(cc1)Nn2c3ccccc3nn2
|
|
|
375
|
CN(Cc1[nH]c(=O)cc(n1)N)S(=O)(=O)c2ccccc2
|
|
|
376
|
c1ccc(cc1)c2nn(c(=O)o2)CN3CCOCC3
|
|
|
377
|
Cc1cc(no1)n2cnc(n2)c3cnoc3C
|
|
|
378
|
CCNc1nnc(s1)Cn2c3ccccc3nn2
|
|
|
379
|
c1ccnc(c1)c2ccc(s2)NC(=O)N3CCOCC3
|
|
|
380
|
Cc1ccc(cn1)Oc2nc3ccccc3o2
|
|
|
381
|
Cc1c(n2c(c1C(=O)NCc3ccccc3)NC(=O)CC2)C
|
|
|
382
|
|
|
|
383
|
c1cc(sc1)CC(=O)Nn2cnnc2
|
|
|
384
|
CN(C)C(=O)N=c1[nH]c2ccccc2[nH]1
|
|
|
385
|
Cn1c(ncn1)COc2cccc(n2)Cl
|
|
|
386
|
c1c(nn[nH]1)SCc2nnc(n2N)CSc3cn[n-]n3
|
|
|
387
|
CC(C)S(=O)(=O)c1c(c(=O)[nH]s1)c2ccccc2
|
|
|
388
|
CC1=C(NC(=O)[C@@H](NC1=O)c2ccccc2)C
|
|
|
389
|
CCOC(=O)N/C=CNC(=O)OCC
|
|
|
390
|
Cn1c(ccn1)/C=C/c2ncc(s2)C(=O)OC
|
|
|
391
|
Cc1ccc(cc1)S(=O)(=O)c2csc(n2)C
|
|
|
392
|
CC1(/C(=C(Nc2ccccn2)/O)/C(=O)c3ccccc3S1)C
|
|
|
393
|
Cc1c(c(no1)c2ccccc2)c3ccn[nH]3
|
|
|
394
|
|
|
|
395
|
c1ccc(cc1)c2cn(c(=O)o2)c3ccccc3
|
|
|
396
|
Cc1c(nc(o1)c2ccccc2)C(=O)/N=c/3[nH]nc4n3cccc4
|
|
|
397
|
c1ccc(cc1)COC(=O)Nc2ccc(=O)[nH]n2
|
|
|
398
|
C1CCC(CC1)COC(=O)N2C[C@@H]3CC[C@H]2CC(=O)O3
|
|
|
399
|
|
|
|
400
|
CCCc1nc(c(s1)C(=O)Nn2cnc3c2cccc3)C
|
|
|
401
|
c1ccc(cc1)n2c(noc2=O)c3cccnc3
|
|
|
402
|
|
|
|
403
|
CN1CC(=C(C1=O)O)c2ccc(cn2)Cc3ccc(cc3)F
|
|
|
404
|
c1ccc(cc1)C#CNCCOc2ccccn2
|
|
|
405
|
c1ccc2c(c1)-c3c(c[nH]n3)CO2
|
|
|
406
|
c1cc(oc1c2[nH]c3cc4c(cc3n2)[nH]c(=O)[nH]4)[C@@H]5CCCCO5
|
|
|
407
|
CC(=O)N1C=Cc2ccccc2[C@@H]1c3c[nH]c4c3cccc4
|
|
|
408
|
c1cc(cnc1)COC(=O)n2ccnc2
|
|
|
409
|
Cc1c(csn1)NC(=O)OC(C)(C)C
|
|
|
410
|
c1ccc(cc1)c2cc(on2)Cn3cnc(n3)C#N
|
|
|
411
|
c1ccc(cc1)n2nc3c(n2)-c4c(non4)CC3
|
|
|
412
|
Cc1nc(cs1)c2ccc3c(c2)oc(=O)[nH]3
|
|
|
413
|
CC(C)(C)OC(=O)n1cc2c(c1)CC(C2)C(=O)[O-]
|
|
|
414
|
C1COCCN1C2=NN3C(=CC(=C4C=CC(=O)C=C4)N3)S2
|
|
|
415
|
CC[C@@H](C(=O)/N=c/1[nH]cn[nH]1)Oc2ccccc2
|
|
|
416
|
c1ccc(cc1)[C@@H]2C=C(OC(=N2)N)c3ccccc3
|
|
|
417
|
Cc1c(c(sn1)C)Nc2c(c(ncn2)SC)C#N
|
|
|
418
|
c1cc(cnc1)c2ccnn2CN3CCOCC3
|
|
|
419
|
CNC1C(=O)NC(SN1)N2CNC3C2CCCC3
|
|
|
420
|
c1cc(ccc1SCCCCn2cncn2)Cl
|
|
|
421
|
c1cn(nc1CC(C(F)(F)F)(C(F)(F)F)O)C(=O)N
|
|
|
422
|
c1ccc(cc1)S[C@@H]2c3ccccc3C(=O)O2
|
|
|
423
|
Cc1nc(cs1)C/C(=N/c2[nH]ncn2)/[O-]
|
|
|
424
|
Cc1c2c([nH]c(=O)n(c2=O)Nc3ccc(cc3)O)sn1
|
|
|
425
|
c1ccc2c(c1)nnn2C3=[NH+]CCN3
|
|
|
426
|
c1ccc-2c(c1)-c3cccc4c3c2n[nH]c4=O
|
|
|
427
|
c1ccc(cc1)[C@@H]2C=CNC(=N2)Nc3nc4ccccc4o3
|
|
|
428
|
c1ccc(c(c1)c2nc([nH]n2)CC(=O)[O-])O
|
|
|
429
|
C1CC(C(=O)N(C1)CC2NNC(O2)C3CC3)C(F)(F)F
|
|
|
430
|
c1ccc(cc1)/C/2=N/c3ccccc3NC(=O)c4c2cccc4
|
|
|
431
|
c1cnn(c1)Cc2nn3c(nnc3s2)C4CC4
|
|
|
432
|
c1cnccc1c2csc(n2)c3cnc[nH]3
|
|
|
433
|
c1ccc(cc1)NC(=O)Nn2cncn2
|
|
|
434
|
c1ccc(cc1)c2c3c([nH]n2)CCC3
|
|
|
435
|
CS(=O)(=O)N[C@@H]1CC(=O)N(C1)c2ccccc2
|
|
|
436
|
c1ccc2c(c1)c(c3c(n2)C[C@@H]4CCCN3C4)C(=O)[O-]
|
|
|
437
|
CSc1nccc(n1)Sc2cn[nH]n2
|
|
|
438
|
c1ccc(cc1)n2c(nnn2)Cn3cnc(n3)C#N
|
|
|
439
|
CN(Cc1ccc(s1)Cl)Cn2cc(nn2)C(=O)OC
|
|
|
440
|
Cc1cc2n(n1)[C@@H](CC(=N2)O)C(=O)Nc3ccccc3F
|
|
|
441
|
CNC(=O)N[C@@H]1[C@H]([C@@H]([C@@H](O1)CO)O)O
|
|
|
442
|
c1cc(oc1)C(=O)N[C@@H]2CC(=O)c3c2ccs3
|
|
|
443
|
c1ccc(cc1)c2c[nH]c3c2c(ncn3)N
|
|
|
444
|
CCc1nnc(c2n1ccc2)N3CCC(CC3)C(=O)[O-]
|
|
|
445
|
|
|
|
446
|
c1ccc2cc(ccc2c1)NC(=O)Sc3[n-]cnn3
|
|
|
447
|
Cc1nc(cs1)c2nc(no2)c3ccc(cc3)CO
|
|
|
448
|
CCNC(=O)Nc1nc2cc(ccn2n1)c3cccnc3
|
|
|
449
|
c1ccc2c(c1)C[C@@H]3[C@H]([C@@H]2/C=C/c4ccccn4)COC3=O
|
|
|
450
|
c1ccc(cc1)c2cc3c(nccn3n2)Cl
|
|
|
451
|
COc1ccc(cc1)c2nc(c(=O)[nH]n2)Cc3ccco3
|
|
|
452
|
Cc1nnc(o1)c2csc(n2)c3cccnc3
|
|
|
453
|
c1cc([nH]c1)c2[nH][nH]c(=O)n2
|
|
|
454
|
c1ccc(cc1)c2cc(nc(n2)C(=O)Nc3[n-]nnn3)O
|
|
|
455
|
c1ccc(cc1)c2c(c3ccc(nc3[nH]2)C(=O)[O-])C4CCCCC4
|
|
|
456
|
Cc1nc2cc([nH]c2c(n1)N3CCC=CC3)c4ccccc4
|
|
|
457
|
Cc1[nH]cc(n1)c2ccccc2
|
|
|
458
|
Cc1nc(c(o1)n2cnc3c2cccc3)C#N
|
|
|
459
|
c1ccc(cc1)n2c(nnn2)Cn3c(nnn3)C4CCCC4
|
|
|
460
|
Cn1c(ccn1)CNC(=O)Cn2cccnc2=O
|
|
|
461
|
Cc1cc(n(n1)CCc2nc(on2)c3ccccc3)C
|
|
|
462
|
Cc1cc(c(=O)n(c1)Cc2cccc(c2)F)NS(=O)(=O)C
|
|
|
463
|
Cc1c(c(n(n1)Cc2nc(cs2)C(C)(C)C)C)Br
|
|
|
464
|
Cc1c(sc(n1)Cn2c3ccccc3nn2)C
|
|
|
465
|
c1ccc2c(c1)[nH]c(n2)Sc3c(non3)N
|
|
|
466
|
c1ccc2c(c1)c(=O)[nH]n(c2=O)C(=O)c3c(non3)N
|
|
|
467
|
C[C@@H](n1ccnc1)OCc2ccc(cc2)F
|
|
|
468
|
c1ccc2c(c1)nnn2CC#C[C@@H](c3ccco3)O
|
|
|
469
|
Cc1csc(n1)Cc2nc3ccccc3n2C
|
|
|
470
|
CCS(=O)(=O)Nc1cnn(c1C)C
|
|
|
471
|
C1CCC(C(C1)C(=O)N)N[C@@H](/C=C/C2CCCO2)C#N
|
|
|
472
|
C1CCC(CC1)CNS(=O)(=O)CC2=N[C@@H]3C=CC=C[C@@H]3N=C2
|
|
|
473
|
CC(C)NC(=O)N[C@H]1COCCO1
|
|
|
474
|
c1ccc(cc1)OC(=O)N2CC(=CC=C2)CO
|
|
|
475
|
|
|
|
476
|
c1ccc(c(c1)OCC(=O)c2ccc[nH]2)F
|
|
|
477
|
C1CCC(CC1)CON2CCCC2C#N
|
|
|
478
|
Cc1c2c(c(=O)n(nn2)CC(=O)NC)n(n1)C
|
|
|
479
|
Cc1[nH]c(c[nH+]1)c2ccnc(n2)SC
|
|
|
480
|
c1ccc2c(c1)nc(s2)Cc3cn4ccccc4n3
|
|
|
481
|
c1ccc(cc1)c2c3c([nH]n2)OC(=O)C[C@@H]3c4ccccc4
|
|
|
482
|
CCc1nc([nH]n1)NC(=O)c2c(n[nH]n2)c3ccccc3
|
|
|
483
|
CC(C)(C)OC(=O)N[C@H](Cc1ccn[nH]1)C(=O)[O-]
|
|
|
484
|
C1CC[C@H](NCC1)N/C=C/C2=CCCCC2
|
|
|
485
|
c1cc2c(cc1C(F)(F)F)nc(s2)c3csnn3
|
|
|
486
|
CC(C)NC(=O)c1ccc(o1)c2cncnc2
|
|
|
487
|
C#CCCNc1c(=O)n(cc(n1)Cl)Cc2ccccc2
|
|
|
488
|
|
|
|
489
|
c1ccnc(c1)NS(=O)(=O)c2ccc(o2)C(=O)[O-]
|
|
|
490
|
c1cc(cc(c1)OCc2cscn2)N
|
|
|
491
|
Cc1nc([nH]n1)SCc2nc(nc(n2)N)N
|
|
|
492
|
C[C@@]1(C(OC(=O)N1CCc2c[nH+]c[nH]2)(C)C)O
|
|
|
493
|
C/C(=C/CO)/C#CCN1CCCC1
|
|
|
494
|
c1c(nc[nH]1)C2(CCCC2)O
|
|
|
495
|
CSc1nc([nH]n1)/N=C([O-])/Oc2ccccc2
|
|
|
496
|
c1ccc2c(c1)NC(N2)[C@@H]3CCC=CO3
|
|
|
497
|
Cc1c2ccc3c(c2oc(=O)c1Br)[nH]c(=O)o3
|
|
|
498
|
Cn1cc(c(n1)c2ccncc2)c3ccc4c(c3)C(=O)NC4
|
|
|
499
|
Cc1c(cnn1C)CCc2nnc(o2)SC
|
|
|
500
|
c1ccc2c(c1)CCN2CCCc3nnc4n3CCCCC4
|
|
|
501
|
c1ccc(cc1)[C@@H]2C3=C(c4ccccc4CC3)NC(=O)N2
|
|
|
502
|
CN1C(=O)C(=C(C12CCC2)N)S(=O)(=O)c3ccc(cc3)Cl
|
|
|
503
|
c1ccc(cc1)S(=O)(=O)Nn2cnnc2
|
|
|
504
|
c1cc(ccc1NC(=O)Cc2[n-]nnn2)F
|
|
|
505
|
CCSc1nnc(n1C)CSc2c([nH]c3c2cccc3)C
|
|
|
506
|
CC(C)(C)c1nc(on1)Cn2cnc(n2)C#N
|
|
|
507
|
COc1ccccc1C/C=C/c2cccs2
|
|
|
508
|
Cc1cc(n(n1)CSc2ccccc2)C
|
|
|
509
|
CC1(CCc2c(ccc3c2cc(o3)c4ccccn4)O1)C
|
|
|
510
|
c1ccc2c(c1)nc(o2)Cn3cnc(n3)C#N
|
|
|
511
|
CC(=O)NC1=C(N=C2N=CC=CN2C1)c3ccccc3
|
|
|
512
|
c1ccc2c(c1)c(ncn2)N3CCNc4c3cccc4
|
|
|
513
|
C1C=CN2[C@H]1[C@@H](C2=O)[C@@H]3[C@@H]4CC=CN4C3=O
|
|
|
514
|
CC1NC([NH]N1)SCCN2CCCN2
|
|
|
515
|
COC(=O)NS(=O)(=O)C1=Cc2cccc3c2c1ccc3
|
|
|
516
|
C[C@@]1(COC(=N1)COc2ccccc2)CO
|
|
|
517
|
c1ccc(cc1)c2ncc(o2)COC(=O)n3ccc(=O)[nH]c3=O
|
|
|
518
|
c1ccc2c(c1)nnn2C3=NCCCC3
|
|
|
519
|
c1ccc(cc1)S(=O)(=O)Nc2[n-]cnn2
|
|
|
520
|
CS(=O)(=O)Nc1cccc2c1cn[nH]2
|
|
|
521
|
c1cn(cn1)OCCCCC(=O)[O-]
|
|
|
522
|
C1CCC2C(C1)[C@@H](CCS2)NC3CNCC(N3)CL
|
|
|
523
|
C[C@@H](c1nc(no1)Cc2cccs2)n3cccn3
|
|
|
524
|
c1ccc(cc1)c2nnc(o2)OCc3nc4ccccc4s3
|
|
|
525
|
c1ccc2c(c1)ncc(n2)n3cnc(n3)C#N
|
|
|
526
|
Cc1c(c(n[nH]1)O)C2=NCCCCC2
|
|
|
527
|
Cn1c(nnc1SC)CSc2ncccn2
|
|
|
528
|
CCC(=O)n1c2ccccc2c3c1Nc4ccccc4N3
|
|
|
529
|
C/C=C/N1[C@H]2C=C[C@@H](C1=O)C(=C2C(=O)OC)C(=O)OC
|
|
|
530
|
CC1NC2C(CN(N2)CC3CCCCC3)C(=O)O1
|
|
|
531
|
CN1C(CCC1C2=N[C@@H](C=C2)C3CCCCC3)C4CCCCC4
|
|
|
532
|
Cc1c[nH]/c(=NC(=O)OC(C)(C)C)/[nH]1
|
|
|
533
|
c1ccc(cc1)c2c(c(=O)c2=O)NCc3cccs3
|
|
|
534
|
c1ccc(cc1)OCCn2ccnc2
|
|
|
535
|
c1ccc(cc1)n2c(nnc2[O-])c3cccnc3
|
|
|
536
|
c1cc(oc1)c2[nH]c3cnn(c3n2)C4CCCC4
|
|
|
537
|
CCC1NNC(O1)COC(=O)C2CC[NH]N2
|
|
|
538
|
CC(C)[C@@H]1NC(=O)C2CCCCC2S1
|
|
|
539
|
CC1(OC[C@H]([C@H](O1)c2cccnc2)C/C=CCCC(=O)[O-])C
|
|
|
540
|
CNC(=O)n1c(ccn1)c2ccc(o2)c3ccc(cc3F)F
|
|
|
541
|
Cc1cnc(o1)Cn2cnc3c2cccc3
|
|
|
542
|
COc1ccc(cc1OC)/C=C/c2nc(on2)c3ccccc3O
|
|
|
543
|
CN1CC[C@@H](c2c1cccc2)n3c4ccccc4nn3
|
|
|
544
|
c1ccc(cc1)c2nc(co2)Cn3nc(nn3)c4ccco4
|
|
|
545
|
CCOC(=O)c1c(c2c(nc(nc2n1C)c3ccccc3)C)N
|
|
|
546
|
Cc1cc(c(c(c1)O)c2c(c[nH]n2)c3nc(cs3)C)O
|
|
|
547
|
Cc1cc(nc2c1c(nn2C)n3c(c(nn3)C#N)N)C
|
|
|
548
|
c1ccc(cc1)n2c(nnn2)Sc3nnc4n3cccc4
|
|
|
549
|
c1ccc(cc1)CSc2ccsc2
|
|
|
550
|
C[C@H]1OC[C@@H]([C@@H](O1)/C=C/C(=C/C(=O)OC)/C)O
|
|
|
551
|
c1cc2c(cc1Cl)ncn3c2nn(c3=O)CC(=O)N
|
|
|
552
|
c1ccc(cc1)N2CCN(CC2)Cc3nnnn3Cc4ccco4
|
|
|
553
|
c1ccc(cc1)N2CCCn3c4ccccc4nc3C2
|
|
|
554
|
c1csc(c1Cl)c2c[nH]c(c2C#N)N
|
|
|
555
|
Cc1c2c(nnc(c2[nH]n1)Cc3ccco3)C
|
|
|
556
|
c1ccc(cc1)c2cc([nH]c(=O)n2)Cc3ccc4ccccc4n3
|
|
|
557
|
CSc1cc(oc1C(=O)c2ccco2)c3ccco3
|
|
|
558
|
c1cc(cc(c1)N)c2c3c(c4n2CCC4)c(=O)[nH]nc3[O-]
|
|
|
559
|
C1CCC(CC1)C(=O)/C(=C/2NN=C3N2CCCCC3)/C#N
|
|
|
560
|
CC1=NN(C(=O)C1)CCc2cccc(c2OC)OC
|
|
|
561
|
C1CC(CC(C1)BR)C2CN3CNSC3N2
|
|
|
562
|
CCn1cc(cn1)c2cc[nH]n2
|
|
|
563
|
|
|
|
564
|
Cc1c(c2nnn(n2n1)CCO)c3ccccc3
|
|
|
565
|
CC(C)c1c2c(n[nH]1)-c3ccccc3C2
|
|
|
566
|
Cc1cc(no1)CNc2nccc(n2)OC
|
|
|
567
|
c1ccc(cc1)S(=O)(=O)Nc2cc3cnnn3c(n2)N
|
|
|
568
|
c1ccc-2c(c1)-c3cccc4c3c2cnc4
|
|
|
569
|
COc1ccnc(n1)N2CCn3c4ccccc4cc3C2
|
|
|
570
|