Structure of IDP95479

2.25 Angstrom Crystal Structure of S-adenosylhomocysteinase from Cryptosporidium parvum in Complex with Neplanocin-A and NAD.

Edit deposit information
CSGID target
IDP95479 
PDB Id
5JXW (NCBI MMDB
Authors
G.Minasov,L.Shuvalova,O.Kiryukhina,I.Dubrovska,B.Bishop,K.Kwon,W.F.Anderson,Center For Structural Genomics Of Infectious Diseases (Csgid) 
Responsible person
George Minasov 
Responsible lab
Northwestern University 
Deposition Date
May 13, 2016 
Release Date
May 25, 2016 

Annotation

Ligands

Ligand code Name Ligand type
NAD biological
GOL crystallization
P6G hexaethylene glycol crystallization
TRS Tris(hydroxymethyl)aminomethane crystallization
175 3,5-dihydro-5-methylidene-4h-imidazol-4-on

Structure information

Unit cell parameters

Space Group
P 1 21 1  
Unit Cell

a=70.89Å, b=136.49Å, c=107.81Å
α=90.00, β=95.73, γ=90.00 
Solvent content
 
Matthews coefficient
 

Refinement

Data for the highest resolution shell is in parentheses.
Resolution range
29.93-2.25Å (2.31-2.25Å)  
Rall(%)
17.6 
Rwork(%)
17.3 (39.1) 
Rfree(%)
22.1 (43.2) 
Num. observed reflections
96260 (6945) 
Num. Rfree reflections
4813 (384) 
Completeness(%)
99.6 (98.0) 

Model parameters

Num Atoms
15487  
Num Waters
754  
Num Hetatoms
1097  
Model mean isotropic B factor
48.580Å2  
RMSD bond length
0.008Å  
RMSD bond angle
1.469°  
Filename uploaded
5jxw.pdb (uploaded on Jul 17, 2016 7:32 PM)  
Inserted
Jul 17, 2016