Publications

<< previous | 1 | 2 |
    2018
  1. Target: IDP92102, IDP92076, IDP92040, :
    Joseph D. Lykins, Ekaterina V. Filippova, Andrei S. Halavaty, George Minasov, Ying Zhou, Ievgeniia Dubrovska, Kristin J. Flores, Ludmilla A. Shuvalova, Jiapeng Ruan, Kamal El Bissati, Sarah Dovgin, Craig W. Roberts, Stuart Woods, Jon D. Moulton, Hong Moulton, Martin J. McPhillie, Stephen P. Muench, Colin W. G. Fishwick, Elisabetta Sabini, Dhanasekaran Shanmugam, David S. Roos, Rima McLeod, Wayne F. Anderson, and Huân M. Ngô (2018)
    CSGID Solves Structures and Identifies Phenotypes for Five Enzymes in Toxoplasma gondii
    Accounts of Chemical Research,8: (Details) (Abstract)
  2. Filippova EV, Zemaitaitis B, Aung T, Wolfe AJ, Anderson WF (2018)
    Structural Basis for DNA Recognition by the Two-Component Response Regulator RcsB.
    mBio,9:e01993-17 (Details) (Abstract)
    Times cited: 0
  3. Luong TT, Tirgar R, Reardon-Robinson ME, Joachimiak A, Osipiuk J, Ton-That H (2018)
    Structural Basis of a Thiol-Disulfide Oxidoreductase in the Hedgehog-Forming Actinobacterium Corynebacterium matruchotii.
    Journal of Bacteriology,200: (Details) (Abstract)
  4. Chang C, Amer BR, Osipiuk J, McConnell SA, Huang IH, Hsieh V, Fu J, Nguyen HH, Muroski J, Flores E, Ogorzalek Loo RR, Loo JA, Putkey JA, Joachimiak A, Das A, Clubb RT, Ton-That H (2018)
    In vitro reconstitution of sortase-catalyzed pilus polymerization reveals structural elements involved in pilin cross-linking.
    Proceedings of the National Academy of Sciences of the United States of America,115:E5477-E5486 (Details) (Abstract)
    Times cited: 1
  5. Chacko S, Boshoff HIM, Singh V, Ferraris DM, Gollapalli DR, Zhang M, Lawson AP, Pepi MJ, Joachimiak A, Rizzi M, Mizrahi V, Cuny GD, Hedstrom L (2018)
    Expanding Benzoxazole-Based Inosine 5''-Monophosphate Dehydrogenase (IMPDH) Inhibitor Structure-Activity As Potential Antituberculosis Agents.
    Journal of Medicinal Chemistry,61:4739-4756 (Details) (Abstract)
    Times cited: 0
  6. Mishra RPN, Yadav RP, Jones C, Nocadello S, Minasov G, Shuvalova LA, Anderson WF, Goel A (2018)
    Structural and immunological characterization of
    Bioscience reports,: (Details) (Abstract)
  7. Gokey T, Halavaty AS, Minasov G, Anderson WF, Kuhn ML (2018)
    Structure of the Bacillus anthracis dTDP-l-rhamnose biosynthetic pathway enzyme: dTDP-α-d-glucose 4,6-dehydratase, RfbB.
    Journal of Structural Biology,202:175-181 (Details) (Abstract)
    Times cited: 0
  8. Kowiel M, Brzezinski D, Porebski PJ, Shabalin IG, Jaskolski M, Minor W (2018)
    Automatic Recognition of Ligands in Electron Density by Machine Learning.
    Bioinformatics,: (Details) (Abstract)
  9. Target: IDP01441, IDP01493:
    Hou J, Zheng H, Tzou WS, Cooper DR, Chruszcz M, Chordia MD, Kwon K, Grabowski M, Minor W (2018)
    Differences in substrate specificity of V. cholerae FabH enzymes suggest new approaches for the development of novel antibiotics and biofuels.
    FEBS Journal,: (Details) (Abstract)
  10. Handing KB, Niedzialkowska E, Shabalin IG, Kuhn ML, Zheng H, Minor W (2018)
    Characterizing metal-binding sites in proteins with X-ray crystallography.
    Nature Protocols,13:1062-1090 (Details) (Abstract)
    Times cited: 1
  11. Target: IDP91189, IDP95778:
    Cox G, Ejim L, Stogios PJ, Koteva K, Bordeleau E, Evdokimova E, Sieron AO, Savchenko A, Serio AW, Krause KM, Wright GD (2018)
    Plazomicin retains antibiotic activity against most aminoglycoside modifying enzymes.
    ACS infectious diseases,: (Details) (Abstract)
  12. Target: IDP95742:
    Stogios PJ, Cox G, Zubyk HL, Evdokimova E, Wawrzak Z, Wright GD, Savchenko A (2018)
    Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis.
    ACS Chemical Biology,: (Details) (Abstract)
  13. Target: IDP92725:
    Nocek B, Reidl C, Starus A, Heath T, Bienvenue D, Osipiuk J, Jedrzejczak R, Joachimiak A, Becker DP, Holz RC (2018)
    Structural Evidence of a Major Conformational Change Triggered by Substrate Binding in DapE Enzymes: Impact on the Catalytic Mechanism.
    Biochemistry,57:574-584 (Details) (Abstract)
    Times cited: 1
  14. Porebski PJ, Sroka P, Zheng H, Cooper DR, Minor W (2018)
    Molstack-Interactive visualization tool for presentation, interpretation, and validation of macromolecules and electron density maps.
    Protein Science,27:86-94 (Details) (Abstract)
    Times cited: 4
  15. Target: IDP96175:
    Koteva K, Cox G, Kelso JK, Surette MD, Zubyk HL, Ejim L, Stogios P, Savchenko A, Sørensen D, Wright GD (2018)
    Rox, a Rifamycin Resistance Enzyme with an Unprecedented Mechanism of Action.
    Cell chemical biology,: (Details) (Abstract)
  16. Target: IDP91794, IDP95086:
    Pawlowski AC, Stogios PJ, Koteva K, Skarina T, Evdokimova E, Savchenko A, Wright GD (2018)
    The evolution of substrate discrimination in macrolide antibiotic resistance enzymes.
    Accounts of Chemical Research,9:112 (Details) (Abstract)
    Times cited: 4
  17. 2017
  18. Tan K, Deatherage Kaiser BL, Wu R, Cuff M, Fan Y, Bigelow L, Jedrzejczak RP, Adkins JN, Cort JR, Babnigg G, Joachimiak A (2017)
    Insights into PG-binding, conformational change, and dimerization of the OmpA C-terminal domains from Salmonella enterica serovar Typhimurium and Borrelia burgdorferi.
    Protein Science,26:1738-1748 (Details) (Abstract)
    Times cited: 1
  19. Ngô HM, Zhou Y, Lorenzi H, Wang K, Kim TK, Zhou Y, El Bissati K, Mui E, Fraczek L, Rajagopala SV, Roberts CW, Henriquez FL, Montpetit A, Blackwell JM, Jamieson SE, Wheeler K, Begeman IJ, Naranjo-Galvis C, Alliey-Rodriguez N, Davis RG, Soroceanu L, Cobbs C, Steindler DA, Boyer K, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Withers S, Soteropoulos P, Hood L, McLeod R (2017)
    Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer.
    Scientific reports,7:11496 (Details) (Abstract)
    Times cited: 8
  20. Zheng H, Langner KM, Shields GP, Hou J, Kowiel M, Allen FH, Murshudov G, Minor W (2017)
    Data mining of iron(II) and iron(III) bond-valence parameters, and their relevance for macromolecular crystallography.
    Acta crystallographica. Section D, Structural biology,73:316-325 (Details) (Abstract)
    Times cited: 3
  21. Target: IDP95418, IDP95403, IDP95031:
    Xu Z, Stogios PJ, Quaile AT, Forsberg KJ, Patel S, Skarina T, Houliston S, Arrowsmith C, Dantas G, Savchenko A (2017)
    Structural and Functional Survey of Environmental Aminoglycoside Acetyltransferases Reveals Functionality of Resistance Enzymes.
    ACS Chemical Biology,3:653-665 (Details) (Abstract)
    Times cited: 0
  22. Reidl C, Majorek KA, Dang J, Tran D, Jew K, Law M, Payne Y, Minor W, Becker DP, Kuhn ML (2017)
    Generating enzyme and radical-mediated bisubstrates as tools for investigating Gcn5-related N-acetyltransferases.
    FEBS Letters,591:2348-2361 (Details) (Abstract)
    Times cited: 0
  23. Target: CPX_06552_06553:
    Wellington S, Nag PP, Michalska K, Johnston SE, Jedrzejczak RP, Kaushik VK, Clatworthy AE, Siddiqi N, McCarren P, Bajrami B, Maltseva NI, Combs S, Fisher SL, Joachimiak A, Schreiber SL, Hung DT (2017)
    A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase.
    Nature Chemical Biology,13:943-950 (Details) (Abstract)
    Times cited: 20
  24. Zheng H, Porebski PJ, Grabowski M, Cooper DR, Minor W (2017)
    Databases, Repositories, and Other Data Resources in Structural Biology.
    Methods in Molecular Biology,1607:643-665 (Details) (Abstract)
    Times cited: 0
  25. Zheng H, Cooper DR, Porebski PJ, Shabalin IG, Handing KB, Minor W (2017)
    CheckMyMetal: a macromolecular metal-binding validation tool.
    Acta crystallographica. Section D, Structural biology,73:223-233 (Details) (Abstract)
    Times cited: 26
  26. Target: IDP01002:
    Kim T, Flick R, Brunzelle J, Singer A, Evdokimova E, Brown G, Joo JC, Minasov GA, Anderson WF, Mahadevan R, Savchenko A, Yakunin AF (2017)
    Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies.
    Applied and environmental microbiology,83:UNSP e03172-16 (Details) (Abstract)
    Times cited: 1
  27. Target: IDP05250, IDP95722:
    Light SH, Cahoon LA, Mahasenan KV, Lee M, Boggess B, Halavaty AS, Mobashery S, Freitag NE, Anderson WF (2017)
    Transferase Versus Hydrolase: The Role of Conformational Flexibility in Reaction Specificity.
    Structure,25:295-304 (Details) (Abstract)
    Times cited: 3
  28. Biancucci M, Dolores JS, Wong J, Grimshaw S, Anderson WF, Satchell KJ, Kwon K (2017)
    New ligation independent cloning vectors for expression of recombinant proteins with a self-cleaving CPD/6xHis-tag.
    BMC Biotechnology,17:1 (Details) (Abstract)
    Times cited: 1
  29. Lee H, Ren J, Nocadello S, Rice AJ, Ojeda I, Light S, Minasov G, Vargas J, Nagarathnam D, Anderson WF, Johnson ME (2017)
    Identification of novel small molecule inhibitors against NS2B/NS3 serine protease from Zika virus.
    Antiviral research,139:49-58 (Details) (Abstract)
    Times cited: 30
  30. Target: IDP91869, IDP91868:
    Stogios PJ, Kuhn ML, Evdokimova E, Law M, Courvalin P, Savchenko A (2017)
    Structural and Biochemical Characterization of Acinetobacter spp. Aminoglycoside Acetyltransferases Highlights Functional and Evolutionary Variation among Antibiotic Resistance Enzymes.
    ACS infectious diseases,3:132-143 (Details) (Abstract)
    Times cited: 3
  31. 2016
  32. Sapparapu G, Fernandez E, Kose N, Cao B, Fox JM, Bombardi RG, Zhao HY, Nelson CA, Bryan AL, Barnes T, Davidson E, Mysorekar IU, Fremont DH, Doranz BJ, Diamond MS, Crowe JE (2016)
    Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice.
    Nature,540:443-447 (Details) (Abstract)
    Times cited: 124
  33. Ghasemi R, Lazear E, Wang X, Arefanian S, Zheleznyak A, Carreno BM, Higashikubo R, Gelman AE, Kreisel D, Fremont DH, Krupnick AS (2016)
    Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy.
    Nature communications,7:12878 (Details) (Abstract)
    Times cited: 10
  34. Majorek KA, Osinski T, Tran DT, Revilla A, Anderson WF, Minor W, Kuhn ML (2016)
    Insight into the 3D structure and substrate specificity of previously uncharacterized GNAT superfamily acetyltransferases from pathogenic bacteria.
    Biochimica et biophysica acta,1865:55-64 (Details) (Abstract)
    Times cited: 1
  35. Grabowski M, Langner KM, Cymborowski M, Porebski PJ, Sroka P, Zheng H, Cooper DR, Zimmerman MD, Elsliger MA, Burley SK, Minor W (2016)
    A public database of macromolecular diffraction experiments.
    Acta crystallographica. Section D, Structural biology,72:1181-1193 (Details) (Abstract)
    Times cited: 20
  36. Target: IDP05250, IDP95184, IDP95187, IDP95188, IDP95722:
    Light SH, Cahoon LA, Halavaty AS, Freitag NE, Anderson WF (2016)
    Structure to function of an α-glucan metabolic pathway that promotes Listeria monocytogenes pathogenesis.
    Nature microbiology,2:16202 (Details) (Abstract)
    Times cited: 3
  37. Target: idp91817:
    Filippova EV, Wawrzak Z, Ruan J, Pshenychnyi S, Schultz RM, Wolfe AJ, Anderson WF (2016)
    Crystal structure of nonphosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli.
    Protein Science,25:2216-2224 (Details) (Abstract)
    Times cited: 6
  38. Target: IDP95734:
    Zhao H, Fernandez E, Dowd KA, Speer SD, Platt DJ, Gorman MJ, Govero J, Nelson CA, Pierson TC, Diamond MS, Fremont DH (2016)
    Structural Basis of Zika Virus-Specific Antibody Protection.
    Cell,166:1016-1027 (Details) (Abstract)
    Times cited: 126
  39. Target: IDP91652:
    Kuhn ML, Alexander E, Minasov G, Page HJ, Warwrzak Z, Shuvalova L, Flores KJ, Wilson DJ, Shi C, Aldrich CC, Anderson WF (2016)
    Structure of the Essential Mtb FadD32 Enzyme: A Promising Drug Target for Treating Tuberculosis.
    ACS infectious diseases,2:579-591 (Details) (Abstract)
    Times cited: 7
  40. Nocadello S, Minasov G, Shuvalova LS, Dubrovska I, Sabini E, Anderson WF (2016)
    Crystal structures of the SpoIID lytic transglycosylases essential for bacterial sporulation.
    Journal of Biological Chemistry,291:14915-26 (Details) (Abstract)
    Times cited: 5
  41. Target: IDP95066:
    Stogios PJ, Cox G, Spanogiannopoulos P, Pillon MC, Waglechner N, Skarina T, Koteva K, Guarné A, Savchenko A, Wright GD (2016)
    Rifampin phosphotransferase is an unusual antibiotic resistance kinase.
    Nature communications,7:11343 (Details) (Abstract)
    Times cited: 9
  42. Filippova EV, Kieser KJ, Luan CH, Wawrzak Z, Kiryukhina O, Rubin EJ, Anderson WF (2016)
    Crystal structures of the transpeptidase domain of the Mycobacterium tuberculosis penicillin-binding protein PonA1 reveal potential mechanisms of antibiotic resistance.
    FEBS Journal,283:2206-18 (Details) (Abstract)
    Times cited: 6
  43. Manjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A (2016)
    Fluorescence-based thermal shift data on multidrug regulator AcrR from Salmonella enterica subsp. entrica serovar Typhimurium str. LT2.
    Data in brief,7:537-9 (Details) (Abstract)
    Times cited: 0
  44. Grabowski M, Niedzialkowska E, Zimmerman MD, Minor W (2016)
    The impact of structural genomics: the first quindecennial.
    Journal of Structural and Functional Genomics,17:1-16 (Details) (Abstract)
    Times cited: 12
  45. Niedzialkowska E, Gasiorowska O, Handing KB, Majorek KA, Porebski PJ, Shabalin IG, Zasadzinska E, Cymborowski M, Minor W (2016)
    Protein purification and crystallization artifacts: The tale usually not told.
    Protein Science,25:720-33 (Details) (Abstract)
    Times cited: 8
  46. Target: IDP00617, IDP00812:
    Nocadello S, Minasov G, Shuvalova L, Dubrovska I, Sabini E, Bagnoli F, Grandi G, Anderson WF (2016)
    Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
    Acta crystallographica. Section D, Structural biology,72:113-120 (Details) (Abstract)
    Times cited: 4
  47. Light SH, Krishna SN, Minasov G, Anderson WF (2016)
    An Unusual Cation-Binding Site and Distinct Domain-Domain Interactions Distinguish Class II Enolpyruvylshikimate-3-Phosphate Synthases.
    Biochemistry,55:1239-45 (Details) (Abstract)
    Times cited: 3
  48. Weigand S, Filippova EV, Kiryukhina O, Anderson WF (2016)
    Small angle X-ray scattering data and structure factor fitting for the study of the quaternary structure of the spermidine N-acetyltransferase SpeG.
    Data in brief,6:47-52 (Details) (Abstract)
    Times cited: 0
  49. Target: IDP02616:
    Manjasetty BA, Halavaty AS, Luan CH, Osipiuk J, Mulligan R, Kwon K, Anderson WF, Joachimiak A (2016)
    Loop-to-helix transition in the structure of multidrug regulator AcrR at the entrance of the drug-binding cavity.
    Journal of Structural Biology,194:18-28 (Details) (Abstract)
    Times cited: 2
  50. 2015
  51. Target: IDP92622:
    Kim Y, Makowska-Grzyska M, Gorla SK, Gollapalli DR, Cuny GD, Joachimiak A, Hedstrom L (2015)
    Structure of Cryptosporidium IMP dehydrogenase bound to an inhibitor with in vivo antiparasitic activity.
    Acta crystallographica. Section F, Structural biology communications,71:531-8 (Details) (Abstract)
    Times cited: 5
  52. Target: IDP92725:
    Starus A, Nocek B, Bennett B, Larrabee JA, Shaw DL, Sae-Lee W, Russo MT, Gillner DM, Makowska-Grzyska M, Joachimiak A, Holz RC (2015)
    Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril.
    Biochemistry,54:4834-44 (Details) (Abstract)
    Times cited: 5
  53. Nelson CA, Epperson ML, Singh S, Elliott JI, Fremont DH (2015)
    Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily.
    Viruses,7:4873-4893 (Details) (Abstract)
    Times cited: 9
  54. Target: IDP90557:
    Hou J, Zheng H, Chruszcz M, Zimmerman MD, Shumilin IA, Osinski T, Demas M, Grimshaw S, Minor W (2015)
    Dissecting the Structural Elements for the Activation of β-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.
    Journal of Bacteriology,198:463-76 (Details) (Abstract)
    Times cited: 6
  55. Target: IDP91646:
    Makowska-Grzyska M, Kim Y, Gorla SK, Wei Y, Mandapati K, Zhang M, Maltseva N, Modi G, Boshoff HI, Gu M, Aldrich C, Cuny GD, Hedstrom L, Joachimiak A (2015)
    Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds.
    PLoS ONE,10:e0138976 (Details) (Abstract)
    Times cited: 10
  56. Target: idp01616:
    Filippova EV, Weigand S, Osipiuk J, Kiryukhina O, Joachimiak A, Anderson WF (2015)
    Substrate induced allosteric change in the quaternary structure of the spermidine N-acetyltransferase SpeG
    Journal of Molecular Biology,427:3538-53 (Details) (Abstract)
    Times cited: 2
  57. Stacy R, Anderson WF, Myler PJ (2015)
    Structural Genomics Support for Infectious Disease Drug Design.
    ACS infectious diseases,1:127-129 (Details) (Abstract)
    Times cited: 2
  58. Zheng H, Handing KB, Zimmerman MD, Shabalin IG, Almo SC, Minor W (2015)
    X-ray crystallography over the past decade for novel drug discovery - where are we heading next?
    Expert opinion on drug discovery,10:975-89 (Details) (Abstract)
    Times cited: 21
  59. Shabalin I, Dauter Z, Jaskolski M, Minor W, Wlodawer A (2015)
    Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin.
    Acta Crystallographica Section D: Biological Crystallography,71:1965-79 (Details) (Abstract)
    Times cited: 24
  60. Target: IDP91046:
    Meziane-Cherif D, Stogios PJ, Evdokimova E, Egorova O, Savchenko A, Courvalin P (2015)
    Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.
    mBio,6:e00806-15 (Details) (Abstract)
    Times cited: 4
  61. Target: IDP91809:
    Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK (2015)
    An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions.
    Cell reports,11:376-89 (Details) (Abstract)
    Times cited: 44
  62. Target: IDP0699:
    Halavaty AS, Rich RL, Chen C, Joo JC, Minasov G, Dubrovska I, Winsor JR, Myszka DG, Duban M, Shuvalova L, Yakunin AF, Anderson WF (2015)
    Structural and functional analysis of betaine aldehyde dehydrogenase from Staphylococcus aureus.
    Acta Crystallographica Section D: Biological Crystallography,71:1159-1175 (Details) (Abstract)
    Times cited: 4
  63. Zheng H, Shabalin IG, Handing KB, Bujnicki JM, Minor W (2015)
    Magnesium-binding architectures in RNA crystal structures: validation, binding preferences, classification and motif detection.
    Nucleic Acids Research,43:3789-801 (Details) (Abstract)
    Times cited: 24
  64. Target: IDP01178 , IDP04364, IDP04376, IDP90781:
    Magdalena Makowska-Grzyska, Youngchang Kim, Natalia Maltseva, Jerzy Osipiuk, Minyi Gu, Minjia Zhang, Kavitha Mandapati, Deviprasad R. Gollapalli, Suresh Kumar Gorla, Lizbeth Hedstrom, Andrzej Joachimiak (2015)
    A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
    Journal of Biological Chemistry,290:5893-5911 (Details) (Abstract)
    Times cited: 15
  65. Target: IDP91779:
    Stogios PJ, Evdokimova E, Morar M, Koteva K, Wright GD, Courvalin P, Savchenko A (2015)
    Structural and functional plasticity of antibiotic resistance nucleotidylyltransferases revealed by molecular characterization of lincosamide nucleotidylyltransferases Lnu(A) and Lnu(D).
    Journal of Molecular Biology,427:2229-43 (Details) (Abstract)
    Times cited: 4
  66. Target: IDP01908:
    Mulder DT, McPhee JB, Reid-Yu SA, Stogios PJ, Savchenko A, Coombes BK (2015)
    Multiple histidines in the periplasmic domain of the Salmonella enterica sensor kinase SsrA enhance signaling in response to extracellular acidification.
    Molecular Microbiology,95:678-91 (Details) (Abstract)
    Times cited: 12
  67. Target: IDP90293:
    Ruan J, Mouveaux T, Light SH, Minasov G, Anderson WF, Tomavo S, Ngô HM (2015)
    The structure of bradyzoite-specific enolase from Toxoplasma gondii reveals insights into its dual cytoplasmic and nuclear functions.
    Acta Crystallographica Section D: Biological Crystallography,71:417-426 (Details) (Abstract)
    Times cited: 9
  68. Target: IDP01616:
    Filippova EV, Kuhn ML, Osipiuk J, Kiryukhina O, Joachimiak A, Ballicora MA, Anderson WF (2015)
    A novel polyamine allosteric site of SpeG from Vibrio cholerae is revealed by its dodecameric structure.
    Journal of Molecular Biology,427:1316-34 (Details) (Abstract)
    Times cited: 8
  69. Target: IDP01169:
    Hammerstrom TG, Horton LB, Swick MC, Joachimiak A, Osipiuk J, Koehler TM (2015)
    Crystal structure of Bacillus anthracis virulence regulator AtxA and effects of phosphorylated histidines on multimerization and activity.
    Molecular Microbiology,95:426-41 (Details) (Abstract)
    Times cited: 15
  70. Target: IDP92558:
    Cox G, Stogios PJ, Savchenko A, Wright GD (2015)
    Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2″)-Ia.
    mBio,6:UNSP e02180-14 (Details) (Abstract)
    Times cited: 12
  71. Target: IDP95069:
    Tyson GH, Halavaty AS, Kim H, Geissler B, Agard M, Satchell KJ, Cho W, Anderson WF, Hauser AR (2015)
    A Novel Phosphatidylinositol 4,5-Bisphosphate Binding Domain Mediates Plasma Membrane Localization of ExoU and Other Patatin-like Phospholipases.
    Journal of Biological Chemistry,290:2919-37 (Details) (Abstract)
    Times cited: 10
  72. 2014
  73. Target: IDP92622:
    Sun Z, Khan J, Makowska-Grzyska M, Zhang M, Cho JH, Suebsuwong C, Vo P, Gollapalli DR, Kim Y, Joachimiak A, Hedstrom L, Cuny GD (2014)
    Synthesis, in vitro evaluation and cocrystal structure of 4-oxo-[1]benzopyrano[4,3-c]pyrazole Cryptosporidium parvum inosine 5''-monophosphate dehydrogenase (CpIMPDH) inhibitors.
    Journal of Medicinal Chemistry,57:10544-50 (Details) (Abstract)
    Times cited: 14
  74. AbouElfetouh A, Kuhn ML, Hu LI, Scholle MD, Sorensen DJ, Sahu AK, Becher D, Antelmann H, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ (2014)
    The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.
    MicrobiologyOpen,4:66-83 (Details) (Abstract)
    Times cited: 36
  75. Target: IDP90300:
    Tonkin, M.L., Halavaty, A.S., Ramaswamy, R., Ruan, J., Igarashi, M., Ngô, H.M. and Boulanger, M.J. (2014)
    Structural and functional divergence of the aldolase fold in Toxoplasma gondii
    Journal of Molecular Biology,427:840-52 (Details) (Abstract)
    Times cited: 6
  76. Target: IDP92725:
    Nocek B, Starus A, Makowska-Grzyska M, Gutierrez B, Sanchez S, Jedrzejczak R, Mack JC, Olsen KW, Joachimiak A, Holz RC (2014)
    The dimerization domain in DapE enzymes is required for catalysis.
    PLoS ONE,9:e93593 (Details) (Abstract)
    Times cited: 6
  77. Majorek KA, Kuhn ML, Chruszcz M, Anderson WF, Minor W (2014)
    Double trouble-Buffer selection and His-tag presence may be responsible for nonreproducibility of biomedical experiments.
    Protein Science,23:1359-68 (Details) (Abstract)
    Times cited: 25
  78. Target: IDP91546:
    Stogios PJ, Kuhn ML, Evdokimova E, Courvalin P, Anderson WF, Savchenko A (2014)
    Potential for reduction of streptogramin A resistance revealed by structural analysis of acetyltransferase VatA.
    Antimicrobial agents and chemotherapy,58:7083-92 (Details) (Abstract)
    Times cited: 2
  79. Vorontsov II, Wu Y, DeLucia M, Minasov G, Mehrens J, Shuvalova L, Anderson WF, Ahn J (2014)
    Mechanisms of allosteric activation and inhibition of the deoxyribonucleoside triphosphate triphosphohydrolase from Enterococcus faecalis.
    Journal of Biological Chemistry,289:2815-24 (Details) (Abstract)
    Times cited: 6
  80. Target: IDP02154:
    Hoyland CN, Aldridge C, Cleverley RM, Duchêne MC, Minasov G, Onopriyenko O, Sidiq K, Stogios PJ, Anderson WF, Daniel RA, Savchenko A, Vollmer W, Lewis RJ (2014)
    Structure of the LdcB LD-Carboxypeptidase Reveals the Molecular Basis of Peptidoglycan Recognition.
    Structure,22:949-60 (Details) (Abstract)
    Times cited: 19
  81. Edeling MA, Diamond MS, Fremont DH (2014)
    Structural basis of Flavivirus NS1 assembly and antibody recognition.
    Proceedings of the National Academy of Sciences of the United States of America,111:4285-90 (Details) (Abstract)
    Times cited: 47
  82. Edeling MA, Austin SK, Shrestha B, Dowd KA, Mukherjee S, Nelson CA, Johnson S, Mabila MN, Christian EA, Rucker J, Pierson TC, Diamond MS, Fremont DH (2014)
    Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement.
    PLos Pathogens,10:e1004072 (Details) (Abstract)
    Times cited: 19
  83. Target: 91809:
    Brown CS, Lee MS, Leung DW, Wang T, Xu W, Luthra P, Anantpadma M, Shabman RS, Melito LM, Macmillan KS, Borek DM, Otwinowski Z, Ramanan P, Stubbs AJ, Peterson DS, Binning JM, Tonelli M, Olson MA, Davey RA, Ready JM, Basler CF, Amarasinghe GK (2014)
    In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity.
    Journal of Molecular Biology,426:2045-58 (Details) (Abstract)
    Times cited: 28
  84. Target: IDP91829, IDP91830:
    Kuhn ML, Zemaitaitis B, Hu LI, Sahu A, Sorensen D, Minasov G, Lima BP, Scholle M, Mrksich M, Anderson WF, Gibson BW, Schilling B, Wolfe AJ (2014)
    Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
    PLoS ONE,9:e94816 (Details) (Abstract)
    Times cited: 109
  85. Target: IDP00699:
    Chen C, Joo JC, Brown G, Stolnikova E, Halavaty AS, Savchenko A, Anderson WF, Yakunin AF (2014)
    Structure-based mutational studies of substrate inhibition of betaine aldehyde dehydrogenase BetB from Staphylococcus aureus.
    Applied and environmental microbiology,80:3992-4002 (Details) (Abstract)
    Times cited: 13
  86. Makowska-Grzyska M, Kim Y, Maltseva N, Li H, Zhou M, Joachimiak G, Babnigg G, Joachimiak A (2014)
    Protein Production for Structural Genomics Using E. coli Expression.
    Methods in Molecular Biology,1140:89-105 (Details) (Abstract)
    Times cited: 7
  87. Tan K, Kim Y, Hatzos-Skintges C, Chang C, Cuff M, Chhor G, Osipiuk J, Michalska K, Nocek B, An H, Babnigg G, Bigelow L, Joachimiak G, Li H, Mack J, Makowska-Grzyska M, Maltseva N, Mulligan R, Tesar C, Zhou M, Joachimiak A (2014)
    Salvage of failed protein targets by reductive alkylation.
    Methods in Molecular Biology,1140:189-200 (Details) (Abstract)
    Times cited: 2
  88. Binkowski TA, Jiang W, Roux B, Anderson WF, Joachimiak A (2014)
    Virtual high-throughput ligand screening.
    Methods in Molecular Biology,1140:251-61 (Details) (Abstract)
    Times cited: 2
  89. Target: IDP91778, IDP91774:
    Meziane-Cherif D, Stogios PJ, Evdokimova E, Savchenko A, Courvalin P (2014)
    Structural basis for the evolution of vancomycin resistance D,D-peptidases.
    Proceedings of the National Academy of Sciences of the United States of America,111:5872-7 (Details) (Abstract)
    Times cited: 13
  90. Target: IDP91568:
    Halavaty AS, Anderson SM, Wawrzak Z, Kudritska M, Skarina T, Anderson WF, Savchenko A. (2014)
    Type III Effector NleH2 from Escherichia coli O157:H7 str. Sakai Features an Atypical Protein Kinase Domain
    Biochemistry,53:2433-2435 (Details) (Abstract)
    Times cited: 4
  91. Target: IDP90163:
    Ratia K, Light SH, Antanasijevic A, Anderson WF, Caffrey M, Lavie A (2014)
    Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase.
    PLoS ONE,9:e89356 (Details) (Abstract)
    Times cited: 7
  92. Luan CH, Light SH, Dunne SF, Anderson WF (2014)
    Ligand screening using fluorescence thermal shift analysis (FTS).
    Methods in Molecular Biology,1140:263-89 (Details) (Abstract)
    Times cited: 3
  93. Minasov G, Anderson WF (2014)
    Structure determination, refinement, and validation.
    Methods in Molecular Biology,1140:239-49 (Details) (Abstract)
    Times cited: 0
  94. Skarina T, Xu X, Evdokimova E, Savchenko A (2014)
    High-throughput crystallization screening.
    Methods in Molecular Biology,1140:159-68 (Details) (Abstract)
    Times cited: 5
  95. Nelson CA, Lee CA, Fremont DH (2014)
    Oxidative refolding from inclusion bodies.
    Methods in Molecular Biology,1140:145-57 (Details) (Abstract)
    Times cited: 5
  96. Shuvalova L (2014)
    Parallel protein purification.
    Methods in Molecular Biology,1140:137-43 (Details) (Abstract)
    Times cited: 1
  97. Nelson CA, McCoy WH, Fremont DH (2014)
    Eukaryotic expression systems for structural studies.
    Methods in Molecular Biology,1140:107-16 (Details) (Abstract)
    Times cited: 0
  98. Kwon K, Peterson SN (2014)
    Expression and solubility testing in a high-throughput environment.
    Methods in Molecular Biology,1140:75-88 (Details) (Abstract)
    Times cited: 0
  99. Kwon K, Peterson SN (2014)
    High-throughput cloning for biophysical applications.
    Methods in Molecular Biology,1140:61-74 (Details) (Abstract)
    Times cited: 5
  100. Yeats C, Dessailly BH, Glass EM, Fremont DH, Orengo CA (2014)
    Target selection for structural genomics of infectious diseases.
    Methods in Molecular Biology,1140:35-51 (Details) (Abstract)
    Times cited: 0
  101. Osman KT, Edwards A (2014)
    Structural genomics of human proteins.
    Methods in Molecular Biology,1140:27-34 (Details) (Abstract)
    Times cited: 1
  102. Zimmerman MD, Grabowski M, Domagalski MJ, Maclean EM, Chruszcz M, Minor W (2014)
    Data management in the modern structural biology and biomedical research environment.
    Methods in Molecular Biology,1140:1-25 (Details) (Abstract)
    Times cited: 12
  103. Light SH, Minasov G, Duban ME, Anderson WF (2014)
    Adherence to Bürgi-Dunitz stereochemical principles requires significant structural rearrangements in Schiff-base formation: insights from transaldolase complexes.
    Acta Crystallographica Section D: Biological Crystallography,70:544-552 (Details) (Abstract)
    Times cited: 9
  104. Target: IDP02095:
    Light SH, Anderson WF (2014)
    Arabinose 5-phosphate covalently inhibits transaldolase.
    Journal of Structural and Functional Genomics,15:41-4 (Details) (Abstract)
    Times cited: 5
change view

Page 1 of 2, showing 100 records out of 161 total, starting on record 1, ending on 100

Pmid Authors Title Journal Issn Year Vol Pages Center Target Pdb Type Times Cited
change view


<< previous | 1 | 2 |