Center for Structural Genomics of Infectious Diseases

CSGID has determined multiple structures from SARS-CoV-2, the coronavirus causing the COVID-19 disease and has also contributed to development of novel coronavirus research resources. CSGID scientists have created tool for visualisation and analysis of the SARS-CoV-2 protein structures with respect to mutational patterns. CSGID researchers are also participating in a consortium developing database of validated SARS-CoV-2 structural models providing accurate, carefully validated structures of potential drug targets.

CSGID is a consortium of laboratories using state-of-the-art structural biology methods to determine the 3-D structures of proteins from pathogens in the NIAID Category A-C priority lists and organisms causing emerging and re-emerging infectious diseases. We do this as a free service to the scientific community! Members of the scientific community are encouraged to submit their targets of interest to CSGID by using our online form: Submit/check your proposal now!
For more detailed information about our mission, please refer to the CSGID brochure (pdf) and the Overview.


May 2020: CSGID work on structures of protein from SARS-CoV-2 has been featured in an article in Nature.
April, 2020: CSGID researchers have determined multiple proteins structures from SARS-CoV-2, the coronavirus causing COVID-19. This research has identified a new potential drug target for the SARS CoV-2 virus

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CSGID is Soliciting Requests from the Scientific Community for Protein Structure Determination

This project has been funded in whole or in part with Federal funds from the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Department of Health and Human Services, under Contracts No. HHSN272200700058C, HHSN272201200026C, and HHSN272201700060C.